Zyvana M2 Tablet SR
Manufacturer
Converge Biotech
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Zyvana M2 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Zyvana M2 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyvana M2 Tablet SR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Zyvana M2 Tablet SR.
Breastfeeding Warning
Zyvana M2 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Zyvana M2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Zyvana M2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zyvana M2 Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Zyvana M2 Tablet SR?
Keep this medicine in its original container or package, tightly closed. Store it as directed on the label or packaging. Dispose of unused medication to prevent access by children, pets, and other individuals.
Can Zyvana M2 Tablet SR lead to lactic acidosis?
Yes, using Zyvana M2 Tablet SR can increase the risk of lactic acidosis. This is a rare side effect caused by the accumulation of lactic acid in the blood. It's also known as MALA (Metformin-associated lactic acidosis). It's considered harmful for patients with kidney disease, older adults or those consuming large amounts of alcohol.
What is Zyvana M2 Tablet SR?
Zyvana M2 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This combination is used to treat type 2 diabetes mellitus (DM). It helps lower blood glucose levels in adults when taken alongside a healthy diet and regular exercise. Glimepiride works by increasing insulin release from the pancreas, while Metformin reduces glucose production from the liver and enhances insulin sensitivity.
What are the possible side effects of Zyvana M2 Tablet SR?
Common side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may include lactic acidosis.
Can the use of Zyvana M2 Tablet SR cause Vitamin B12 deficiency?
Yes, long-term use of Zyvana M2 Tablet SR can lead to vitamin B12 deficiency. It interferes with the absorption of vitamin B12 from the stomach. If not addressed, it can result in anemia and nerve problems. Patients may experience tingling in hands and feet, weakness, urinary difficulties, changes in mental status, and difficulty maintaining balance (ataxia). To prevent these complications, some experts recommend supplementing Vitamin B12 from external sources at least once per year.
Can Zyvana M2 Tablet SR lead to hypoglycemia?
Yes, using Zyvana M2 Tablet SR can cause hypoglycemia (low blood sugar levels). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It is more likely if you miss meals, drink alcohol, over-exercise, or take other antidiabetic medications at the same time.
Is it safe to take alcohol while taking Zyvana M2 Tablet SR?
No, combining Zyvana M2 Tablet SR with alcohol is not recommended as it may lower blood sugar levels and increase the risk of hypoglycemia. It can also potentially lead to lactic acidosis.
