Zoryl M 0.5 Tablet PR
Manufacturer
Intas Pharmaceuticals Ltd
Salt Composition
Glimepiride (0.5mg) + Metformin (500mg)
Key Information
Short Description
Zoryl M 0.5 Tablet PR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet PR
Introduction
Zoryl M 0.5 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Use it as advised by your doctor or check the label for directions before use. Zoryl M 0.5 Tablet PR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Zoryl M 0.5 Tablet PR may cause a rare but serious condition called lactic acidosis
Alcohol Warning
It is unsafe to consume alcohol with Zoryl M 0.5 Tablet PR.
Breastfeeding Warning
Zoryl M 0.5 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Zoryl M 0.5 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Zoryl M 0.5 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
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Frequently asked questions
What are the recommended storage conditions for Zoryl M 0.5 Tablet PR?
Store this medicine in its original container or pack, tightly closed. Follow the instructions on the packaging label regarding storage. Dispose of unused medication safely and securely to prevent unintended access by pets, children, or other individuals.
Can the use of Zoryl M 0.5 Tablet PR lead to lactic acidosis?
Yes, using Zoryl M 0.5 Tablet PR can increase the risk of lactic acidosis. It is a medical emergency caused by an increase in lactic acid levels in the bloodstream. This is known as MALA (Metformin-associated lactic acidosis). It's important to be aware that this side effect is rare, but it can occur in patients with underlying kidney disease, older adults, or those who consume large quantities of alcohol. Symptoms may include muscle pain or weakness, dizziness, fatigue, coldness in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, and slow heart rate. If you experience these symptoms, discontinue Zoryl M 0.5 Tablet PR and consult your doctor immediately.
What is Zoryl M 0.5 Tablet PR?
Zoryl M 0.5 Tablet PR contains a combination of two medications: Glimepiride and Metformin. This medication is used to manage type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when combined with proper diet and regular exercise. Glimepiride lowers blood sugar by increasing insulin release from the pancreas, while Metformin reduces glucose production in the liver and enhances insulin sensitivity. This combination is not suitable for treating type 1 DM.
What are the possible side effects of Zoryl M 0.5 Tablet PR?
Common side effects of Zoryl M 0.5 Tablet PR include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. The use of this medication can also lead to more serious but rare side effects such as lactic acidosis. On long-term usage, it may cause Vitamin B12 deficiency.
Can the use of Zoryl M 0.5 Tablet PR cause Vitamin B12 deficiency?
Yes, long-term use of Zoryl M 0.5 Tablet PR can lead to a Vitamin B12 deficiency due to interference with vitamin B12 absorption in the stomach. If untreated, this could result in anemia and nerve problems, leading to tingling sensations in the hands and feet, weakness, urinary difficulties, changes in mental status, and difficulties in maintaining balance (ataxia). To prevent these issues, individuals might consider supplementing with Vitamin B12 from external sources at least once a year.
Can the use of Zoryl M 0.5 Tablet PR cause hypoglycemia?
Yes, using Zoryl M 0.5 Tablet PR can lead to hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, and feeling anxious or shaky. This is more likely to occur if you miss meals, drink alcohol excessively, exercise heavily, or take other antidiabetic medications together with it. Therefore, regular blood sugar monitoring is crucial.
Is it safe to consume alcohol while taking Zoryl M 0.5 Tablet PR?
No, consuming alcohol alongside Zoryl M 0.5 Tablet PR is not advisable because it can lead to lower blood sugar levels and a higher chance of hypoglycemia. It may also increase the risk of lactic acidosis.
