Zeformin XR 60 Tablet
Manufacturer
Abbott
Salt Composition
Metformin (500mg) + Gliclazide (60mg)
Key Information
Short Description
Zeformin XR 60 Tablet is an anti-diabetic drug used to treat type 2 diabetes mellitus in adults by controlling blood sugar levels.
Dosage Form
Tablet SR
Introduction
Zeformin XR 60 Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. While effective, it can cause hypoglycemia, especially when used with other antidiabetic medicines, alcohol, or if meals are delayed or missed. It may also cause a rare but serious condition called lactic acidosis. Regular monitoring of liver function and blood sugar levels is advised.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Zeformin XR 60 Tablet is to be taken with food.
How it works
Zeformin XR 60 Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zeformin XR 60 Tablet may cause a rare but serious condition called lactic acidosis. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
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Frequently asked questions
What is Zeformin XR 60 Tablet?
Zeformin XR 60 Tablet is a combination of two medicines: Gliclazide and Metformin. It is used to treat type 2 diabetes mellitus (DM) in adults, improving blood glucose levels when taken with a proper diet and regular exercise. Gliclazide lowers blood glucose levels by increasing insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not suitable for treating Type 1 DM.
What are the possible side effects of Zeformin XR 60 Tablet?
The use of Zeformin XR 60 Tablet is associated with common side effects, including hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rare but serious side effects include lactic acidosis, which can occur on long-term use, leading to vitamin B12 deficiency.
Can the use of Zeformin XR 60 Tablet cause hypoglycemia?
Yes, Zeformin XR 60 Tablet can cause hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Regular monitoring of blood sugar levels is crucial, and it's essential to keep glucose tablets, honey, or fruit juice handy.
Can the use of Zeformin XR 60 Tablet cause lactic acidosis?
Yes, Zeformin XR 60 Tablet can lead to lactic acidosis, a medical emergency caused by increased lactic acid levels in the blood. This rare side effect is associated with metformin use and is more likely to occur in patients with underlying kidney disease, old age, or those who consume large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, stop taking Zeformin XR 60 Tablet and consult your doctor immediately.
Can the use of Zeformin XR 60 Tablet lead to Vitamin B12 deficiency?
Yes, Zeformin XR 60 Tablet can cause vitamin B12 deficiency on long-term use. The medicine interferes with vitamin B12 absorption in the stomach, potentially leading to anemia, nerve problems, and symptoms such as tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty maintaining balance. To avoid these issues, consider taking vitamin B12 supplements at least once a year.
Are there any specific conditions in which Zeformin XR 60 Tablet should not be taken?
Avoid using Zeformin XR 60 Tablet in patients with known allergies to its components or excipients. It is also contraindicated in patients with moderate to severe kidney disease or underlying metabolic acidosis, including diabetic ketoacidosis.
Is it safe to take alcohol while I am also taking Zeformin XR 60 Tablet?
No, it is not safe to consume alcohol while taking Zeformin XR 60 Tablet. This may lower your blood sugar levels (hypoglycemia) and increase the risk of lactic acidosis. Consult your doctor for personalized advice on medication and lifestyle.
