




Trigli 1 Tablet SR
Manufacturer
Ordain Health Care Global Pvt Ltd
Salt Composition
Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (5mg)
Key Information
Short Description
Trigli 1 Tablet SR is a combination medicine that helps control blood sugar levels in adults with type 2 diabetes mellitus.
Dosage Form
Tablet SR
Introduction
Trigli 1 Tablet SR is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Trigli 1 Tablet SR is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Trigli 1 Tablet SR.
Breastfeeding Warning
Trigli 1 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Trigli 1 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Trigli 1 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, Metformin, and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines, and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Quick Tips
Take it with food to lower your chance of having an upset stomach. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
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Frequently asked questions
Can I drink alcohol while taking Trigli 1 Tablet SR?
No, alcohol consumption should be avoided when using Trigli 1 Tablet SR. Alcohol may lower your blood sugar levels (hypoglycemia) and increase the risk of lactic acidosis.
What should I inform the doctor before taking Trigli 1 Tablet SR?
Before taking Trigli 1 Tablet SR, inform your doctor if you have congestive heart failure, kidney problems, liver problems, or swelling of the back of the eye. It is also important to tell your doctor if you are pregnant, breastfeeding, or a premenopausal woman. Inform them about any prescription and non-prescription medications, vitamins, and herbal supplements you may be taking.
Can the use of Trigli 1 Tablet SR lead to Vitamin B12 deficiency?
Yes, using Trigli 1 Tablet SR can increase the risk of vitamin B12 deficiency as it contains metformin. Over time, this drug may interfere with the absorption of vitamin B12 from the stomach.
Can the use of Trigli 1 Tablet SR cause hypoglycemia?
Yes, Trigli 1 Tablet SR can cause hypoglycemia (low blood sugar). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, a rapid heart rate, and feelings of anxiety or shakiness. This is more likely to occur if you miss meals, drink alcohol, exercise excessively, or take other antidiabetic medications alongside it. Regular blood sugar monitoring is necessary to manage this risk. Keep some readily available sugary items like candy or chocolate with you at all times.
What are the instructions for the storage and disposal of Trigli 1 Tablet SR?
Store this medication in its original container, tightly closed, and according to the instructions provided on the packaging. Do not consume any unused medications. It should also be inaccessible to pets, children, and others.