
Trexodat 7.5mg Tablet
Manufacturer
Leeford Healthcare Ltd
Salt Composition
Methotrexate (7.5mg)
Key Information
Short Description
Trexodat 7.5mg Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Trexodat 7.5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trexodat 7.5mg Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hairloss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Trexodat 7.5mg Tablet.
Breastfeeding Warning
Trexodat 7.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Trexodat 7.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Trexodat 7.5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Trexodat 7.5mg Tablet kills cancer cells by preventing them from making DNA. Trexodat 7.5mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Trexodat 7.5mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Trexodat 7.5mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Frequently asked questions
Can Trexodat 7.5mg Tablet cause mouth ulcers?
Yes, Trexodat 7.5mg Tablet can cause a sore mouth and mouth ulcers as side effects in some patients. Taking folic acid along with this medication may help reduce the frequency of these ulcers. It is recommended to consult your doctor if the dose needs adjustment for potential further ulcer reduction.
Why must I take folic acid with Trexodat 7.5mg Tablet?
Folic acid is essential for cell regeneration in the body, and Trexodat 7.5mg Tablet can lower its levels. Folic acid helps alleviate some common side effects of Trexodat 7.5mg Tablet, such as sore mouth, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why do I need to have regular blood tests when taking Trexodat 7.5mg Tablet?
Regular blood tests allow your doctor to track your response to Trexodat 7.5mg Tablet and assess for any side effects. These tests include checking liver function and assessing blood counts (white blood cells, red blood cells, and platelets). Your doctor may order additional tests based on the test results.
Can Trexodat 7.5mg Tablet increase my susceptibility to infections?
Trexodat 7.5mg Tablet might weaken your immune system, potentially leading to increased risk of serious infections. There have been rare cases where Trexodat 7.5mg Tablet use has been associated with severe lung infections. If you are dealing with an active infection, using Trexodat 7.5mg Tablet requires cautious consideration.
Can Trexodat 7.5mg Tablet affect my fertility?
Yes, Trexodat 7.5mg Tablet may impact fertility in both males and females. It might decrease sperm count in men and trigger menstrual irregularities in women. These effects are usually temporary and resolve after the medication is discontinued.
What should I do if I'm planning to become pregnant, and my husband is taking Trexodat 7.5mg Tablet?
You should avoid becoming pregnant while your husband is taking Trexodat 7.5mg Tablet. It is recommended that pregnancy be postponed for at least three months after treatment stops, as it may increase the risk of fetal abnormalities.