Macleods Pharmaceuticals Pvt Ltd
Topiroxostat (20mg)
Topimac 20 Tablet is a medicine used to treat and prevent gout. It lowers the levels of uric acid by stopping its release from the kidneys.
Tablet
Topimac 20 Tablet should be taken with food. This will prevent you from getting an upset stomach. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. Use of this medicine may cause increased liver enzymes in some people. If you experience any other side effects which do not go away with time or bothers you, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose. To make sure the medicine is safe for you, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also let your doctor know all the other medicines you are taking before using this medicine. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topimac 20 Tablet may be taken with or without food but it is better to take it at a fixed time.
No common side effects listed.
It is not known whether it is safe to consume alcohol with Topimac 20 Tablet. Please consult your doctor.
Information regarding the use of Topimac 20 Tablet during breastfeeding is not available. Please consult your doctor.
Information regarding the use of Topimac 20 Tablet during pregnancy is not available. Please consult your doctor.
Gout occurs due to increased blood uric acid levels. Topimac 20 Tablet reduces the synthesis of uric acid by inhibiting the enzyme involved in it.
Take adequate water or fluids while taking Topimac 20 Tablet to prevent kidney stones. Consult your doctor before taking it if you have or ever had kidney stones, stomach ulcers, peptic ulcers, diabetes, liver disorders or blood disorders. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Take adequate water or fluids while taking Topimac 20 Tablet to prevent kidney stones. Treatment with this medicine should not be started during a sudden/severe gout attack. Wait until your current attack is over before starting this medication.
The usual adult dosage of Topimac 20 Tablet is 20 mg/dose orally given twice daily in the morning and evening. The dosage should be gradually increased, as needed, while monitoring blood uric acid levels. The usual maintenance dose should be 60 mg/dose twice daily. The dose may be adjusted based on the patient's condition, up to 80 mg/dose twice daily.
Patients with kidney disease should use Topimac 20 Tablet with caution due to the higher risk of side effects in these patients.
The dose of Topimac 20 Tablet should be increased gradually. The starting dose should be 20 mg/dose twice daily and the dose should be increased gradually, for example, to 40 mg/dose twice daily at or after Week 2, then to 60 mg/dose twice daily at or after Week 6. The patient should be adequately monitored after the dose increase.