Tofe-ER Tablet
Manufacturer
Alkem Laboratories Ltd
Salt Composition
Tofacitinib (11mg)
Key Information
Short Description
Tofe-ER Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis by reducing inflammation and slowing the progression of bone and joint damage.
Dosage Form
Tablet ER
Introduction
Tofe-ER Tablet may be prescribed by itself or in combination with another medicine. The tablets can be taken with or without food and it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse. The most common side effects of Tofe-ER Tablet include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have any worries about side effects, talk to your doctor. You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofe-ER Tablet can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (such as chickenpox, measles, flu). This medicine is not suitable for children under 18 years old and you should not use it if you are pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you regularly.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofe-ER Tablet may be taken with or without food, but it is better to take it at a fixed time.
How it works
Tofe-ER Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme Janus kinase. This decreases the activity of the immune system and inflammation associated with rheumatic diseases and ulcerative colitis.
Quick Tips
Tofe-ER Tablet is used alone or in combination with other medicines for the treatment of rheumatoid arthritis that did not improve with other anti-rheumatic drugs. It may take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed. Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels. Tofe-ER Tablet can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches. Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
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Frequently asked questions
Can I take Tofe-ER Tablet if I have liver problems?
Before taking Tofe-ER Tablet, inform your healthcare provider about any existing liver conditions. It is essential to monitor liver enzymes during treatment. Although Tofe-ER Tablet can be prescribed to patients with mild to moderate liver dysfunction, it should not be given to those with severe liver impairment.
Can Tofe-ER Tablet cause cancer?
Tofe-ER Tablet might increase the risk of developing certain cancers, including lymphoma and skin cancers, by affecting the immune system. If you have a history of cancer or are currently diagnosed with it, inform your doctor about this.
What is Tofe-ER Tablet used for?
Tofe-ER Tablet is prescribed to treat moderate to severe rheumatoid arthritis. This condition affects the joints and causes inflammation. Tofe-ER Tablet is used when previous treatments have not been effective or are not suitable for the individual.
How long does it take for Tofe-ER Tablet to start working?
It typically takes 2 to 8 weeks before you notice any improvement with Tofe-ER Tablet. It can take anywhere from 3 to 6 months to experience the full effect of this medication.
Do I need any investigations before starting Tofe-ER Tablet?
Before starting Tofe-ER Tablet, your doctor may recommend blood tests to check for conditions like anemia, neutropenia, lymphopenia, high cholesterol levels, and liver enzyme abnormalities. These tests are essential for ensuring treatment with Tofe-ER Tablet is safe.
Can Tofe-ER Tablet cause infections?
Tofe-ER Tablet may suppress your immune system, which could weaken your body's ability to fight off infection. This medication can also increase the risk of serious or life-threatening infections, including those caused by bacteria, fungi, and viruses. It is important to seek immediate medical attention if you experience any signs or symptoms of infection after starting Tofe-ER Tablet.
If I am already taking tocilizumab, can I take Tofe-ER Tablet?
No, you should not use both tocilizumab and Tofe-ER Tablet together. These medications work on the immune system, so it is important to avoid using them simultaneously.
