Tofatop 5mg Tablet
Manufacturer
Alkem Laboratories Ltd
Salt Composition
Tofacitinib (5mg)
Key Information
Short Description
Tofatop 5mg Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis by reducing inflammation and slowing the progression of bone and joint damage.
Dosage Form
Tablet
Introduction
Tofatop 5mg Tablet may be prescribed by itself or in combination with another medicine. The tablets can be taken with or without food and it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse. The most common side effects of Tofatop 5mg Tablet include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have any worries about side effects, talk to your doctor. You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofatop 5mg Tablet can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (such as chickenpox, measles, flu). This medicine is not suitable for children under 18 years old and you should not use it if you are pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you regularly.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofatop 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Information
Side Effects
Upper respiratory tract infections Headache Diarrhea Nasopharyngitis Blood clots and tears in the stomach or intestine wall (serious)
Alcohol Warning
Consuming alcohol with Tofatop 5mg Tablet does not cause any harmful side effects.
Breastfeeding Warning
Tofatop 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Tofatop 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Tofatop 5mg Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme Janus kinase. This decreases the activity of the immune system and inflammation associated with rheumatic diseases and ulcerative colitis.
Quick Tips
Tofatop 5mg Tablet is used alone or in combination with other medicines for the treatment of rheumatoid arthritis that did not improve with other anti-rheumatic drugs. It may take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed. Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels. Tofatop 5mg Tablet can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches. Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
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Tofatas 5mg Tablet
Betrecep 5mg Tablet
TFCT-Nib Tablet
Frequently asked questions
Can I take Tofatop 5mg Tablet if I have liver problems?
It is essential to inform your doctor about any liver problems you may have before starting Tofatop 5mg Tablet. This is because Tofatop 5mg Tablet may cause an increase in liver enzymes in some cases. Your doctor will investigate your liver function before starting the medication. While Tofatop 5mg Tablet can be used in patients with mild to moderate liver function impairment, it is not recommended for those with severe liver impairment.
Can Tofatop 5mg Tablet cause cancer?
Tofatop 5mg Tablet may increase the risk of developing certain cancers, such as lymphoma and skin cancers, by affecting the immune system. If you have ever had or have any type of cancer, it is crucial to inform your doctor.
What is Tofatop 5mg Tablet used for?
Tofatop 5mg Tablet is approved for the treatment of moderate to severe rheumatoid arthritis, an inflammatory disease of the joints. It is typically used in patients who have not responded well to previous therapies or who have not tolerated the prescribed medications. Tofatop 5mg Tablet can be used alone or in combination with other medications, such as methotrexate.
How long does it take for Tofatop 5mg Tablet to start working?
Tofatop 5mg Tablet usually takes around 2 to 8 weeks to start showing noticeable improvements, and it can take up to 3 to 6 months to achieve the maximum effect of the medication.
Do I need to get any investigations done before starting Tofatop 5mg Tablet?
You may need to undergo blood tests before starting Tofatop 5mg Tablet or while taking it. These tests help monitor your red blood cell count, white blood cell count, liver enzymes, and cholesterol levels. Your doctor may also recommend testing for tuberculosis before starting Tofatop 5mg Tablet, as it may exacerbate an existing infection.
Can Tofatop 5mg Tablet cause infections?
Tofatop 5mg Tablet affects the immune system, which may reduce your ability to fight infections and increase the risk of developing serious infections, including tuberculosis. In some cases, these infections can be life-threatening and may even cause death. It is essential to seek medical attention if you experience any signs of infection while taking Tofatop 5mg Tablet.
If I am already taking tocilizumab, can I take Tofatop 5mg Tablet?
No, you should not take Tofatop 5mg Tablet along with tocilizumab. Both medications affect the immune system, and taking them together can increase the risk of infection and lead to further complications. It is crucial to consult with your doctor before starting any new medication, especially if you are already taking another immunity-affecting medication.