Solonex 300 Tablet
Manufacturer
Macleods Pharmaceuticals Pvt Ltd
Salt Composition
Isoniazid (300mg)
Key Information
Short Description
Solonex Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB.
Dosage Form
Tablet
Introduction
Solonex Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor as these side effects require medical attention and need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Solonex Tablet is to be taken empty stomach. Avoid Solonex Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Safety Information
Side Effects
tingling and numbness of feet and hand (peripheral neuropathy) jaundice hepatitis (viral infection of the liver) increased liver enzymes stomach pain joint pain
Alcohol Warning
Consuming alcohol while taking Solonex Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Breastfeeding Warning
Solonex Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Pregnancy Warning
Solonex Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Interacting Medicines
Alprazolam Carbamazepine Chlordiazepoxide Clobazam
How it works
Solonex Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.
Quick Tips
It is best taken on an empty stomach. You must also take a vitamin B6 supplement while on Solonex Tablet. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
Frequently asked questions
Is Solonex Tablet an antibiotic?
Solonex Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB, a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body.
Is Solonex Tablet a chemotherapy/chemotherapy drug?
Solonex Tablet is a primary antibiotic used for the treatment of tuberculosis. It should not be confused with chemotherapy or chemo drugs used for the treatment of cancer.
Is Solonex Tablet bacteriostatic or bactericidal?
Solonex Tablet is a bacteriostatic antibiotic. It stops or suppresses the growth of tuberculosis-causing bacteria by interfering with the formation of the protective outer covering (cell wall) which is essential for their growth.
Is Solonex Tablet safe?
Yes, Solonex Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Is Solonex Tablet a MAOI?
Solonex Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however, it is not used as a monoamine oxidase inhibitor (MAOI).
Is Solonex Tablet a sulfa drug?
No, the chemical structure and mechanism of action of Solonex Tablet is different from sulfa drugs.
Is Solonex Tablet an inducer or inhibitor?
Solonex Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body.
Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There are no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin, or any active drug present in Nyquil or Mucinex. However, please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce the effectiveness of any treatment or aggravate side effects.
Does Solonex Tablet cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea, or changes in menstruation are not among the known side effects of Solonex Tablet. You may experience some of these side effects while on multi-drug (including Solonex Tablet) treatment for tuberculosis.
Does Solonex Tablet cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation, or acne while on treatment with Solonex Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce the effectiveness of any treatment or aggravate side effects.
Does Solonex Tablet affect birth control?
Solonex Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.
