Sivel 400mg Tablet
Manufacturer
Sanzyme Ltd
Salt Composition
Sevelamer (400mg)
Key Information
Short Description
Sivel 400mg Tablet is used to treat increased phosphate levels in the blood in patients who are on dialysis due to severe kidney disease.
Dosage Form
Tablet
Introduction
Sivel 400mg Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sivel 400mg Tablet is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is not known whether it is safe to consume alcohol with Sivel 400mg Tablet. Please consult your doctor.
Breastfeeding Warning
Sivel 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pregnancy Warning
Sivel 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Interacting Medicines
Mycophenolate mofetil Tacrolimus Ciclosporin
How it works
Sivel 400mg Tablet inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.
Quick Tips
Sivel 400mg Tablet is used to control blood phosphate level in patients that are on dialysis treatment. You must take it with food and stick to the diet prescribed by your doctor. You may develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Your doctor may prescribe supplements if necessary. Avoid taking any other medicine 1 hour before or 3 hours after taking Sivel 400mg Tablet. Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
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Acutrol C 400mg Tablet
Eusave 400 Tablet
Sevlamin 400 Tablet
Zeesev 400 Tablet
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Frequently asked questions
Is Sivel 400mg Tablet taken with food?
Yes, Sivel 400mg Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sivel 400mg Tablet works by binding to phosphate from food in the digestive tract.
Can Sivel 400mg Tablet be crushed?
No, you should not crush, chew, or break Sivel 400mg Tablet into pieces. You should swallow it as a whole with water.
Why is it important for me to take Sivel 400mg Tablet?
It is important to take Sivel 400mg Tablet because patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sivel 400mg Tablet, as it binds phosphate from food in the digestive tract.
Does Sivel 400mg Tablet cause constipation?
A common side effect of Sivel 400mg Tablet is constipation. However, this does not occur in everyone. Other side effects of the stomach and intestines include diarrhea, indigestion, flatulence, and abdominal pain. If these side effects become severe, consult your doctor immediately.
Who should not take Sivel 400mg Tablet?
Patients who are allergic to Sivel 400mg Tablet and those with low phosphate levels in the blood should avoid taking Sivel 400mg Tablet. Additionally, patients with intestinal obstruction should also avoid using Sivel 400mg Tablet.
Can I take ciprofloxacin while I am taking Sivel 400mg Tablet?
Ciprofloxacin may interfere with the working of Sivel 400mg Tablet and therefore should not be taken at the same time as Sivel 400mg Tablet. However, if taken together, a gap of at least 2 hours before or 6 hours after taking Sivel 400mg Tablet should be maintained.
How long do I need to take Sivel 400mg Tablet?
Continue taking Sivel 400mg Tablet as long as recommended by your doctor. Sivel 400mg Tablet lowers your dietary phosphate levels but does not cure your disease, so you may have to take it lifelong. Stopping Sivel 400mg Tablet may increase your phosphate levels.
Do I need to have any tests while taking Sivel 400mg Tablet?
Yes, serum phosphate levels should be monitored regularly while you are taking Sivel 400mg Tablet. Additionally, the use of Sivel 400mg Tablet may decrease the levels of vitamin D, A, E, K, and folic acid, so their levels need to be monitored during treatment.
