



Saferet 20 Tablet
Manufacturer
Canixa Life Sciences Pvt Ltd
Salt Composition
Isotretinoin (20mg)
Key Information
Short Description
Saferet 20 Tablet belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.
Dosage Form
Tablet
Introduction
Saferet 20 Tablet should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again. The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Saferet 20 Tablet is to be taken with food.
How it works
Saferet 20 Tablet is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).
Quick Tips
You have been prescribed Saferet 20 Tablet for the treatment of severe acne. Take it with food. Avoid exposure to sunlight while using Saferet 20 Tablet. Use protective measures such as sunscreen or protective clothing. Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile. It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
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Frequently asked questions
Is Saferet 20 Tablet safe to use?
Saferet 20 Tablet should be used with caution as it is associated with potential serious adverse reactions. It should only be used for patients with severe nodular acne who have not responded to conventional treatments, including systemic antibiotics. Additionally, Saferet 20 Tablet is contraindicated in pregnant women due to the risk of severe birth defects.
Is Saferet 20 Tablet a steroid?
No, Saferet 20 Tablet is a retinoid (vitamin A) used to treat severe acne.
What tests should be performed during Saferet 20 Tablet therapy?
Pre-treatment liver enzymes and serum lipids will be checked. These levels should be monitored monthly after treatment initiation, with additional monitoring at 3-month intervals unless clinically indicated for more frequent checks.
Is the effect of Saferet 20 Tablet permanent?
Many patients have reported that a single course lasting 15-20 weeks effectively treats the condition and prevents recurrence. If additional treatment is needed, it should be initiated after at least 8 weeks following completion of the initial course. This is because experience with Saferet 20 Tablet has shown that symptoms in acne may continue to improve post-treatment.
Why is Saferet 20 Tablet dangerous during pregnancy?
If pregnancy occurs during treatment with Saferet 20 Tablet, it significantly increases the risk of severe birth defects in the baby. The use of this medication during pregnancy is strongly discouraged.
Can Saferet 20 Tablet cause cancer?
There are no reported cases of Saferet 20 Tablet causing cancer. In fact, it may be used in certain forms of head, skin, and neck cancers.
What are the long-term side effects of Saferet 20 Tablet?
A standard treatment course with Saferet 20 Tablet lasts 15–20 weeks. However, long-term effects of low doses have not been studied. It is possible that this medication may affect bone mineral density. It may lead to decreased bone mineral density in some patients, potentially increasing the risk of osteoporosis or fractures.
Does Saferet 20 Tablet impact male fertility?
No, Saferet 20 Tablet does not negatively affect the fertility of male patients. There have been no significant effects on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.
Does Saferet 20 Tablet damage your liver?
There might be a temporary increase in liver enzymes after starting Saferet 20 Tablet treatment. Regular laboratory tests are essential for monitoring these values. If the levels remain elevated for an extended period, your doctor may consider discontinuing Saferet 20 Tablet.