Safe Gem 1mg/500mg Tablet SR
Manufacturer
Sigmund Promedica
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Safe Gem 1mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Safe Gem 1mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Safe Gem 1mg/500mg Tablet SR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Safe Gem 1mg/500mg Tablet SR.
Breastfeeding Warning
Safe Gem 1mg/500mg Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Safe Gem 1mg/500mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Safe Gem 1mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting and stomach pain as Safe Gem 1mg/500mg Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Safe Gem 1mg/500mg Tablet SR?
Keep this medicine in its original container or pack, tightly closed. Store according to the instructions on the packaging label. Dispose of any unused medicine properly, ensuring it is not accessible to pets, children, and other people.
Can the use of Safe Gem 1mg/500mg Tablet SR lead to lactic acidosis?
Yes, the use of Safe Gem 1mg/500mg Tablet SR can potentially cause lactic acidosis. This is a serious medical condition where there is an increase in lactic acid levels in the blood. It's also known as MALA (Metformin-associated lactic acidosis). It's a rare side effect associated with metformin and is therefore considered to be harmful for patients with underlying kidney disease, elderly individuals, or those consuming high amounts of alcohol.
What is Safe Gem 1mg/500mg Tablet SR?
Safe Gem 1mg/500mg Tablet SR is a combination medication containing two active ingredients: Glimepiride and Metformin. It's specifically used to treat type 2 diabetes mellitus (DM). Glimepiride increases the release of insulin from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity.
What are the possible side effects of Safe Gem 1mg/500mg Tablet SR?
The most common side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. In rare cases, it can cause serious but potentially life-threatening side effects such as lactic acidosis.
Can the use of Safe Gem 1mg/500mg Tablet SR lead to Vitamin B12 deficiency?
Yes, long-term use of Safe Gem 1mg/500mg Tablet SR can potentially contribute to a vitamin B12 deficiency. It interferes with the absorption of Vitamin B12 in the stomach and could result in anemia or neurological problems like tingling and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To minimize this risk, some experts recommend supplementing with Vitamin B12 regularly.
Can the use of Safe Gem 1mg/500mg Tablet SR cause hypoglycemia?
Yes, the use of Safe Gem 1mg/500mg Tablet SR can lead to hypoglycemia (low blood sugar). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, and feeling anxious or shaky. This is more likely if you skip meals, drink alcohol, exercise excessively, or take other antidiabetic medications simultaneously.
Is it safe to drink alcohol while I am also taking Safe Gem 1mg/500mg Tablet SR?
No, drinking alcohol while taking Safe Gem 1mg/500mg Tablet SR is not recommended. Alcohol can lower your blood sugar levels and increase the risk of hypoglycemia (low blood sugar) and lactic acidosis.
