Rifanex 450mg/300mg Tablet

Short Description

Rifanex 450mg/300mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Dosage Form

Tablet

Introduction

Rifanex 450mg/300mg Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken on an empty stomach and at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some time to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve. Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help. Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifanex 450mg/300mg Tablet is to be taken on an empty stomach. Avoid Rifanex 450mg/300mg Tablet with tyramine-rich food such as cheese, smoked fish, meats, and some types of beer.

Side Effects

Nausea Vomiting Fever Dark-colored urine Sweating Increased saliva

Alcohol Warning

Consuming alcohol while taking Rifanex 450mg/300mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Breastfeeding Warning

Rifanex 450mg/300mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Pregnancy Warning

Rifanex 450mg/300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Rifanex 450mg/300mg Tablet is a combination of two antibiotics: Rifampicin and Isoniazid, which treats tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

You have been prescribed Rifanex 450mg/300mg Tablet for the treatment of tuberculosis. Finish the full course of the medication even if you feel better. Stopping it early may make the infection come back. Take it on an empty stomach, preferably at the same time every day. It may discolor your urine, sweat, saliva, and tears a reddish-orange color. This is normal and not harmful. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Avoid drinking alcohol while taking Rifanex 450mg/300mg Tablet as this may increase the risk of side effects on the liver. Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Rifanex 450mg/300mg Tablet as it may make hormonal contraceptives such as the pill less effective. Do not take indigestion remedies (antacids) within at least two hours of taking Rifanex 450mg/300mg Tablet.