R-Cin 450 Capsule
Manufacturer
Lupin Ltd
Salt Composition
Rifampicin (450mg)
Key Information
Short Description
R-Cin 450 Capsule is an antibiotic used to treat all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Dosage Form
Capsule
Introduction
R-Cin 450 Capsule is an antibiotic used to treat all forms of tuberculosis. It may be used alone or in combination with other medicines to fight serious infections. It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food. Your urine, tears, and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Tell your doctor about all other medicines you are taking as R-Cin 450 Capsule can interact with many medicines. Avoid taking hormone-based birth control methods as R-Cin 450 Capsule may decrease their effectiveness. Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. R-Cin 450 Capsule is to be taken empty stomach.
Safety Information
Side Effects
No common side effects listed
Alcohol Warning
It is unsafe to consume alcohol with R-Cin 450 Capsule.
Breastfeeding Warning
R-Cin 450 Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Pregnancy Warning
R-Cin 450 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Interacting Medicines
Aprepitant Atazanavir Eszopiclone Indinavir
How it works
R-Cin 450 Capsule is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by bacteria to make essential proteins and to reproduce.
Quick Tips
Your doctor has prescribed R-Cin 450 Capsule to cure your infection and improve symptoms. It is best taken on an empty stomach. Your urine, tears, and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Tell your doctor about all other medicines you are taking as R-Cin 450 Capsule can interact with many medicines. Avoid taking hormone-based birth control methods as R-Cin 450 Capsule may decrease their effectiveness. Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.
Frequently asked questions
Is rifampin a penicillin/amoxicillin/sulfa drug?
No. Rifampin is an antibiotic used to treat tuberculosis and leprosy. Its structure and mechanism of action are different from penicillins, amoxicillin (which belongs to the penicillin class), and sulfa drugs.
Is rifampin bacteriostatic or bactericidal?
Rifampin is a bactericidal drug. It inhibits DNA-dependent RNA polymerase, an enzyme crucial for bacterial life processes, which ultimately leads to bacterial death.
Is rifampin an inducer or inhibitor?
Rifampin acts as an inducer of a liver enzyme system responsible for metabolizing and eliminating drugs from the body. This process helps ensure that medications are cleared efficiently.
What is R-cin 600 used for?
R-cin 600, a trade name, contains rifampin (600 mg) and is used in the treatment of tuberculosis. It is also used to prevent meningococcal meningitis and Haemophilus influenza infections.
What is R-cinex/Macox plus/R-cinex 600?
R-cinex and Macox plus are trade names for a combination of rifampin and isoniazid. This combination is used to treat tuberculosis.
Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?
There's no known serious drug interaction between rifampin and ibuprofen or acetaminophen (Tylenol). It's important to inform your doctor about all medications you are currently taking to avoid potential interactions that could reduce treatment effectiveness or worsen side effects.
Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?
No. Rifampin is generally well-tolerated and there's no known association with these symptoms. It's important to note that individual experiences may vary.
Does rifampin cause headaches?
Yes, headache can be a possible side effect of rifampin.
Does rifampin change urine color/turn urine orange?
Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears, and feces) to brownish-red or orange. This is usually harmless.
Does rifampin cause liver damage?
Rifampin is generally safe when used at prescribed doses for the prescribed duration. Regular monitoring of liver function is important while on treatment with rifampin. Certain medications like saquinavir and ritonavir can worsen liver issues and may interact negatively.
