Pyzina 500 Tablet
Manufacturer
Lupin Ltd
Salt Composition
Pyrazinamide (500mg)
Key Information
Short Description
Pyzina 500 Tablet is an antibiotic that belongs to a class of medicines known as anti-tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Dosage Form
Tablet
Introduction
Pyzina 500 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyzina 500 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Caution is advised when consuming alcohol with Pyzina 500 Tablet. Please consult your doctor.
Breastfeeding Warning
Pyzina 500 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pregnancy Warning
Pyzina 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Interacting Medicines
Allopurinol
How it works
Pyzina 500 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme) which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.
Quick Tips
Do not forget a dose as this increases the risk of the bacteria becoming resistant to the medicine and also increases the risk of getting side effects. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Avoid drinking alcohol while taking Pyzina 500 Tablet as this may increase the risk of side effects on the liver. Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Pyzina 500 Tablet as it may make hormonal contraceptives such as the pill less effective.
Frequently asked questions
What is Pyzina 500 Tablet and what is it used for?
Pyzina 500 Tablet is an antibiotic medication used in combination with other antibiotics to treat tuberculosis.
Is Pyzina 500 Tablet bactericidal?
Pyzina 500 Tablet exhibits both bacteriostatic and bactericidal properties, meaning it can either stop the growth of bacteria or kill the tuberculosis-causing bacteria, depending on the specific circumstances.
How does Pyzina 500 Tablet work/treat tuberculosis?
Pyzina 500 Tablet is effective against Mycobacterium tuberculosis, the bacteria that causes tuberculosis, although the exact mechanism of action is not fully understood.
How does Pyzina 500 Tablet cause hyperuricemia and gout?
When taken orally, Pyzina 500 Tablet is converted into pyrazinoic acid, its active form, which inhibits the excretion of urates by the kidneys, leading to increased blood levels of uric acid (hyperuricemia). This excess uric acid can accumulate in joints, causing pain, swelling, redness, and stiffness (gout).
