Prenot 75mg/10mg Tablet
Manufacturer
Medcure Pharma
Salt Composition
Pregabalin (75mg) + Nortriptyline (10mg)
Key Information
Short Description
Prenot 75mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
Dosage Form
Tablet
Introduction
Prenot 75mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain. It is used to treat certain types of long-lasting pain caused by damage to nerves.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prenot 75mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Prenot 75mg/10mg Tablet may cause excessive drowsiness with alcohol.
Breastfeeding Warning
Prenot 75mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Prenot 75mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Prenot 75mg/10mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Quick Tips
Prenot 75mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves. Inform your doctor if you are taking any other pain-relieving medicines. Inform your doctor if you have a history of seizures. Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
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Pregeb Nt Tablet
Neurica NT Tablet
Maxgalin NT Tablet
Nortipan Tablet
Nervite Tablet
Pregalin NT Tablet
Frequently asked questions
What is Prenot 75mg/10mg Tablet?
Prenot 75mg/10mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation.
Can I stop taking Prenot 75mg/10mg Tablet when my pain is relieved?
No, you should not stop taking Prenot 75mg/10mg Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Prenot 75mg/10mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the dose before you stop the medication completely.
How to manage weight gain associated with the use of Prenot 75mg/10mg Tablet?
Prenot 75mg/10mg Tablet can make you feel hungry, which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy, balanced diet without increasing your portion sizes (per-meal intake). Do not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables, and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Can the use of Prenot 75mg/10mg Tablet cause sleepiness or drowsiness?
Yes, Prenot 75mg/10mg Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Can the use of Prenot 75mg/10mg Tablet affect my sexual life?
The use of Prenot 75mg/10mg Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity), and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Prenot 75mg/10mg Tablet.
Are there any serious side effects associated with the use of Prenot 75mg/10mg Tablet?
Serious side effects because of Prenot 75mg/10mg Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness, or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat, or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
How long will the Prenot 75mg/10mg Tablet take to act?
An initial benefit with Prenot 75mg/10mg Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
What if I forget to take Prenot 75mg/10mg Tablet?
If you forget to take the scheduled dose of Prenot 75mg/10mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing, and increased heartbeat.
Will Prenot 75mg/10mg Tablet be more effective if a higher than the recommended dosage is taken?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Is there anything I need to avoid while taking Prenot 75mg/10mg Tablet?
Prenot 75mg/10mg Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Prenot 75mg/10mg Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Prenot 75mg/10mg Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Prenot 75mg/10mg Tablet. However, you must consult your doctor if the advised dosage of Prenot 75mg/10mg Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Are there any special instructions regarding the storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
