Pentanerv-NT 400/10 Tablet
Manufacturer
Alkem Laboratories Ltd
Salt Composition
Gabapentin (400mg) + Nortriptyline (10mg)
Key Information
Short Description
Pentanerv-NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
Dosage Form
Tablet
Introduction
Pentanerv-NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain. It is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together they relieve neuropathic pain (pain from damaged nerves).
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentanerv-NT Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Pentanerv-NT Tablet may cause excessive drowsiness with alcohol.
Breastfeeding Warning
Pentanerv-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Pentanerv-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Pentanerv-NT Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together they relieve neuropathic pain (pain from damaged nerves).
Quick Tips
Inform your doctor if you are taking any other pain-relieving medicines. Avoid taking antacids 2 hours before or after taking Pentanerv-NT Tablet as they make it harder for your body to absorb the medicine.
Related Medicines
Gabapin NT Tablet
Neurotab-NT Tablet
Gabastar NT 400mg/10mg Tablet
Gabantin-NT Tablet
Gabaneuron NT 400 Tablet
Gabator NT 400mg/10mg Tablet
Gabatime NT 400mg/10mg Tablet
Nervigra NT Tablet
Bagapen-NT Tablet
Gabarep NT 400mg/10mg Tablet
Frequently asked questions
What is Pentanerv-NT Tablet?
Pentanerv-NT Tablet is a combination medication containing Gabapentin and Nortriptyline. It's used to treat nerve pain (neuropathic pain). This medicine calms the nerves by acting on the brain, reducing pain sensation.
Can I stop taking Pentanerv-NT Tablet when my pain is relieved?
No, you should not stop taking Pentanerv-NT Tablet even if your pain is relieved. Continue to take it as prescribed by your doctor. Stopping abruptly might lead to withdrawal symptoms like anxiety, sleep disturbances, nausea, and sweating. It's important to taper the dose gradually before stopping completely.
How can I manage weight gain associated with Pentanerv-NT Tablet?
Pentanerv-NT Tablet can cause hunger, leading to increased calorie intake. However, maintaining a healthy diet and exercise routine is key for preventing weight gain rather than losing it. Aim for balanced meals without increasing portion sizes. Avoid high-calorie foods like soft drinks, oily food, chips, cakes, biscuits, and sweets. Opt for fruits, vegetables, and low-calorie options instead. Regular exercise will help prevent weight gain.
Does Pentanerv-NT Tablet affect sexual life?
Pentanerv-NT Tablet can impact both men's and women's sexual life. Common side effects include decreased libido, erectile dysfunction (difficulty achieving or maintaining erection during sexual activity), difficulty reaching orgasm, decreased satisfaction, and discomfort during intercourse. If you experience these issues, discuss them with your doctor, but don't stop taking the medication.
Are there any serious side effects associated with Pentanerv-NT Tablet?
Serious side effects of Pentanerv-NT Tablet are uncommon. However, if you notice any: significant changes in body temperature, difficulty breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reaction times, blurred vision, dizziness, body temperature fluctuations, or difficulty breathing and heart rate increase, seek urgent medical attention.
What should I avoid while taking Pentanerv-NT Tablet?
Pentanerv-NT Tablet might impair your thinking or reactions. Be cautious when driving or engaging in activities requiring alertness. Avoid alcohol consumption while on this medication, as it can intensify its effects and lead to dangerous situations. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. It's crucial to protect yourself from the sun and use sunscreen outdoors during daytime. Exposure to sunlight might increase your risk of sunburn.
How often should I see the doctor while taking Pentanerv-NT Tablet?
Regular check-ups are recommended after starting Pentanerv-NT Tablet, especially if your symptoms don't improve. Consult your doctor if you experience any unwanted side effects that impact your daily activities.
Will Pentanerv-NT Tablet make me sleepy?
Yes, Pentanerv-NT Tablet can cause drowsiness or sudden sleep episodes during the day. Avoid driving, operating machinery, working at heights, or engaging in potentially dangerous activities while on this medication until you understand its effects.
Does increasing the dosage of Pentanerv-NT Tablet improve effectiveness?
No, exceeding the recommended dose will not increase effectiveness. Rather, it might increase the likelihood of side effects and toxicity. If your symptoms worsen despite adhering to the prescribed dose, consult your doctor for re-evaluation.
What are the storage conditions for Pentanerv-NT Tablet?
Store Pentanerv-NT Tablet in its original packaging until it's time to take a dose. Keep it in a cool, dry place out of sight and reach of children. Do not dispose of unused medications by throwing them in the regular trash or recycling bin. Follow special instructions provided for disposal.
