Glenmark Pharmaceuticals Ltd
Palbociclib (125mg)
Palbinas 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs.
Capsule
Palbinas 125mg Capsule should be taken with food but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Take this medicine in the dose and duration as advised by your doctor. Palbinas 125mg Capsule is to be taken with food.
No common side effects listed.
It is not known whether it is safe to consume alcohol with Palbinas 125mg Capsule. Please consult your doctor.
Palbinas 125mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Palbinas 125mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Palbinas 125mg Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6 thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.
Take it with food preferably at the same time every day If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose Use effective contraception method to prevent pregnancy while taking this medicine. It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you. You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Do not stop taking the medication without talking to your doctor first.
Palbinas 125mg Capsule is a prescription anti-cancer medication. It blocks proteins known as cyclin-dependent kinase inhibitors.
The duration of treatment varies depending on the individual's cancer type and response to therapy. Your doctor will determine the appropriate number of cycles, considering factors like your condition, treatment response, and tolerability.
Most side effects are temporary and reversible once treatment is discontinued. Neutropenia, a common adverse effect, reduces white blood cell count and weakens the immune system. This can increase the risk of infection; however, it typically resolves quickly after stopping the medication.
Regular blood tests are crucial to monitor potential blood cell effects associated with Palbinas 125mg Capsule. These tests should be performed at the start of each chemotherapy cycle, on days 15 of the first two cycles, and as clinically indicated.
Palbinas 125mg Capsule is typically taken once daily for 21 consecutive days, followed by a 7-day rest period to complete a full cycle of 28 days. Take the capsule with food at the same time each day and swallow it completely. Do not open, chew, or crush the capsule, nor take broken or cracked capsules.
Women of childbearing potential who are receiving Palbinas 125mg Capsule and their partners should use reliable contraceptive methods (e.g., double-barrier contraception such as condoms and diaphragms) during therapy and for at least 3 weeks after completing therapy, for females. Men on Palbinas 125mg Capsule therapy must also use birth control methods for at least 14 weeks after completion of the treatment.
It is important to note that male fertility may be affected during Palbinas 125mg Capsule treatment. Therefore, men are advised to consider sperm preservation prior to initiating therapy.
Palbinas 125mg Capsule can cause serious side effects including difficulty breathing, dizziness, fatigue, unusual bleeding or bruising, nosebleeds. Fever, chills, and fast, irregular heartbeat might also occur. Seek immediate medical attention if experiencing any of these symptoms.