Palbace 75mg Capsule
Manufacturer
Pfizer Ltd
Salt Composition
Palbociclib (75mg)
Key Information
Short Description
Palbace 75mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Dosage Form
Capsule
Introduction
Palbace 75mg Capsule should be taken with food but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Palbace 75mg Capsule is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is not known whether it is safe to consume alcohol with Palbace 75mg Capsule. Please consult your doctor.
Breastfeeding Warning
Palbace 75mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Palbace 75mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Palbace 75mg Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6 thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.
Quick Tips
Take it with food preferably at the same time every day Use effective contraception method to prevent pregnancy while taking this medicine. It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you. You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Do not stop taking the medication without talking to your doctor first.
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Frequently asked questions
What kind of medicine is Palbace 75mg Capsule?
Palbace 75mg Capsule is an anti-cancer medication that blocks proteins known as cyclin-dependent kinase inhibitors. These protein blockers help slow the growth of cancer cells and delay the progression of the disease.
How long do I have to take Palbace 75mg Capsule?
The duration of treatment varies depending on individual needs, response to treatment, and tolerance to side effects. Your doctor will determine the number of cycles you need to receive based on your specific condition.
Are the side effects of Palbace 75mg Capsule irreversible?
Most side effects are reversible and disappear when the medication is stopped. Neutropenia, a decrease in white blood cells, can occur with Palbace 75mg Capsule, leading to increased susceptibility to infection. However, this side effect typically improves rapidly once treatment stops.
Does treatment with Palbace 75mg Capsule require monitoring of blood counts?
Yes, regular blood tests are crucial during treatment as Palbace 75mg Capsule can affect blood cell counts. These tests help monitor the medication's effect on your red blood cells, white blood cells, and platelets. They should be done at the beginning of each chemotherapy cycle, on the 15th day of the first two cycles, and if clinically indicated.
How should I take Palbace 75mg Capsule?
Palbace 75mg Capsule is typically taken once daily for 21 consecutive days, followed by a 7-day rest period. This creates a complete cycle of 28 days. Swallow the whole capsule and avoid opening, chewing, or crushing it. Do not take broken or cracked capsules.
Do I need to use birth control method while using Palbace 75mg Capsule?
Women of childbearing potential should use effective contraception methods (e.g., double-barrier contraception, such as condom and diaphragm) during and after treatment with Palbace 75mg Capsule. Men on treatment should also consider using effective contraceptive methods for at least 14 weeks after completing therapy.
Does Palbace 75mg Capsule affect fertility?
Palbace 75mg Capsule may affect male fertility. Therefore, men considering fertility should consider sperm preservation before starting treatment.
What are the serious side effects of Palbace 75mg Capsule?
Serious side effects include shortness of breath, dizziness, weakness, unusual bleeding or bruising, and nosebleeds. It can also cause fever, chills, signs of infection, and fast, irregular, or pounding heartbeat. Seek medical attention immediately if experiencing these symptoms.
