

Palbace 125mg Tablet
Manufacturer
Pfizer Ltd
Salt Composition
Palbociclib (125mg)
Key Information
Short Description
Palbace 125mg Tablet is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Dosage Form
Tablet
Introduction
Palbace 125mg Tablet should be taken with food but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Palbace 125mg Tablet is to be taken with food.
How it works
Palbace 125mg Tablet is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6 thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.
Quick Tips
Take it with food preferably at the same time every day skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose Use effective contraception method to prevent pregnancy while taking this medicine. It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you. You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Do not stop taking the medication without talking to your doctor first.
Related Medicines
Frequently asked questions
What type of medicine is Palbace 125mg Tablet?
Palbace 125mg Tablet is an anti-cancer medication used to treat certain types of cancer. This medication specifically inhibits proteins known as cyclin-dependent kinase inhibitors, which are involved in the growth and proliferation of cancer cells.
How long do I have to take Palbace 125mg Tablet?
The duration of treatment varies depending on individual factors. Your doctor will determine the number of cycles needed for your specific condition, response to treatment, and tolerability.
Are the side effects of Palbace 125mg Tablet irreversible?
Most side effects are reversible and disappear upon stopping medication. Neutropenia, a decrease in white blood cell count, is commonly reported as an adverse effect. While this can weaken the immune system and increase infection risk, it typically resolves quickly upon discontinuation of Palbace 125mg Tablet.
Does treatment with Palbace 125mg Tablet require monitoring of blood counts?
Yes. Regular blood tests are essential to monitor blood cell counts while taking this medication. These tests check the effects of Palbace 125mg Tablet on your white blood cells, red blood cells, and platelets. Blood testing should be performed at the beginning of each chemotherapy cycle, 15 days into the first two cycles, and as needed by your healthcare provider.
How should I take Palbace 125mg Tablet?
Palbace 125mg Tablet is typically taken once daily for 21 consecutive days followed by a 7-day rest period. This constitutes one complete cycle of treatment that lasts 28 days. It should be taken with food at the same time each day, and swallowed as a whole capsule without opening, chewing, or crushing.
Do I need to use birth control while taking Palbace 125mg Tablet?
Women of childbearing potential who are receiving this medication and their partners should use effective contraception (e.g., double-barrier methods such as condoms and diaphragms) throughout therapy and for at least three weeks after completing treatment. Men on treatment with Palbace 125mg Tablet must use reliable birth control methods for at least 14 weeks following completion of the therapy.
Does Palbace 125mg Tablet affect fertility?
The medication may affect male fertility. Therefore, individuals are advised to consider sperm preservation before starting treatment with Palbace 125mg Tablet. If you are a male experiencing difficulties in conception, discussing the issue with your healthcare provider is advisable.
What are the serious side effects of Palbace 125mg Tablet?
Potential serious side effects include shortness of breath, dizziness, weakness, unusual bleeding or bruising, nosebleeds. Fever, chills, and fast, irregular, or pounding heartbeat should also be reported to your healthcare provider.