P Zide 1000 Tablet
Manufacturer
Cadila Pharmaceuticals Ltd
Salt Composition
Pyrazinamide (1gm)
Key Information
Short Description
P Zide 1000 Tablet is an antibiotic that belongs to a class of medicines known as anti-tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Dosage Form
Tablet
Introduction
P Zide 1000 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P Zide 1000 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Caution is advised when consuming alcohol with P Zide 1000 Tablet. Please consult your doctor.
Breastfeeding Warning
P Zide 1000 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pregnancy Warning
P Zide 1000 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Interacting Medicines
Allopurinol
How it works
P Zide 1000 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme) which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.
Quick Tips
Do not to forget a dose Do not skip any doses and finish the full course of treatment even if you feel better Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking P Zide 1000 Tablet as it may make hormonal contraceptives such as the pill less effective Avoid drinking alcohol while taking P Zide 1000 Tablet as this may increase the risk of side effects on the liver Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain.
Frequently asked questions
What is P Zide 1000 Tablet and what is it used for?
P Zide 1000 Tablet is an antibiotic used to treat tuberculosis, often taken in combination with other antibiotics.
Is P Zide 1000 Tablet bactericidal?
P Zide 1000 Tablet exhibits both bacteriostatic and bactericidal properties. It can inhibit the growth of bacteria (bacteriostatic) in certain cases, but it also actively kills tuberculosis-causing bacteria (bactericidal) in others.
How does P Zide 1000 Tablet work/treat tuberculosis?
P Zide 1000 Tablet targets and eliminates the bacteria responsible for causing tuberculosis (Mycobacterium tuberculosis). However, the exact mechanism of action of P Zide 1000 Tablet is not fully understood.
How does P Zide 1000 Tablet cause hyperuricemia and gout?
Following oral intake of P Zide 1000 Tablet, it undergoes a conversion process in the body to form pyrazinoic acid (the active chemical component of P Zide 1000 Tablet). Pyrazinoic acid disrupts the kidneys' excretion of urates (the salt form of uric acid), resulting in elevated levels of uric acid in the blood (hyperuricemia). This accumulation of excess uric acid leads to joint pain, swelling, redness, and stiffness (gout).
