
Npgab NT 400mg/10mg Tablet
Manufacturer
Mitis Biomedics Ltd
Salt Composition
Gabapentin (400mg) + Nortriptyline (10mg)
Key Information
Short Description
Npgab NT 400mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
Dosage Form
Tablet
Introduction
Npgab NT 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together they relieve neuropathic pain (pain from damaged nerves).
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Npgab NT 400mg/10mg Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Npgab NT 400mg/10mg Tablet may cause excessive drowsiness with alcohol.
Breastfeeding Warning
Npgab NT 400mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Npgab NT 400mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Npgab NT 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together they relieve neuropathic pain (pain from damaged nerves).
Quick Tips
Npgab NT 400mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves. Inform your doctor if you are taking any other pain-relieving medicines. Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain. Avoid taking antacids 2 hours before or after taking Npgab NT 400mg/10mg Tablet as they make it harder for your body to absorb the medicine.
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Gabaneuron NT 400 Tablet

Gabastan NT 400mg/10mg Tablet

Gabalord NT 400mg/10mg Tablet

Gabarv NT 400mg/10mg Tablet
Frequently asked questions
What is Npgab NT 400mg/10mg Tablet?
Npgab NT 400mg/10mg Tablet is a combination medication containing Gabapentin and Nortriptyline. It is used to treat nerve pain (Neuropathic pain) by calming damaged or overactive nerves and reducing pain sensation.
Can I stop taking Npgab NT 400mg/10mg Tablet when my pain is relieved?
No, it is not recommended to stop taking Npgab NT 400mg/10mg Tablet even if your pain is relieved. Stopping the medication abruptly may lead to withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. Consult your doctor for guidance on tapering the dose before stopping the medication.
How to manage weight gain associated with the use of Npgab NT 400mg/10mg Tablet?
Npgab NT 400mg/10mg Tablet may cause increased appetite, which can lead to weight gain. To manage weight gain, try to eat a balanced diet without increasing portion sizes. Avoid consuming high-calorie foods and drinks, such as soft drinks, oily foods, chips, cakes, biscuits, and sweets. Regular exercise can also help prevent weight gain. Maintaining good eating habits and regular exercise may help prevent weight gain.
Can the use of Npgab NT 400mg/10mg Tablet affect my sexual life?
Yes, Npgab NT 400mg/10mg Tablet may affect sexual life in both men and women. Commonly reported problems include decreased sexual desire, erectile dysfunction, and difficulty reaching orgasm. It may also cause decreased satisfaction and discomfort during sexual intercourse. If you experience these problems, discuss them with your doctor, but do not stop taking the medication.
Are there any serious side effects associated with the use of Npgab NT 400mg/10mg Tablet?
Serious side effects associated with Npgab NT 400mg/10mg Tablet are uncommon and rare. If you experience any of the following symptoms, seek immediate medical attention: changes in body temperature, difficulty breathing, increased heartbeat, weakness, unsteadiness when walking, reduced coordination, unusual changes in mood or behavior, signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, or signs of frequent infections.
How long will the Npgab NT 400mg/10mg Tablet take to act?
An initial benefit with Npgab NT 400mg/10mg Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. In some patients, it may take longer to see the full effect.
What if I forget to take Npgab NT 400mg/10mg Tablet?
If you forget to take a dose of Npgab NT 400mg/10mg Tablet and it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. If you remember the missed dose later, take it as soon as you remember and then resume your regular dosing schedule. Do not take a double dose to make up for the missed dose, as this may increase the risk of unwanted side effects.
What if I take too much of this drug by mistake?
In case of an overdose, contact your doctor immediately or seek emergency medical attention. Even if you do not experience any symptoms, it is essential to seek medical attention. Overdose symptoms may include drowsiness, weakness, unsteadiness when walking, double vision, slurred speech, diarrhea, confusion, blurred vision, dizziness, body temperature changes, difficulty breathing, and increased heartbeat.
Is there anything I need to avoid while taking Npgab NT 400mg/10mg Tablet?
Avoid activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you. Avoid drinking alcohol while taking Npgab NT 400mg/10mg Tablet, as it can increase the effects of the medication. Grapefruit and grapefruit juice may also interact with this medication and cause unwanted side effects. Avoid exposure to sunlight or tanning beds, as the medication may make you more prone to sunburns.
How often should I see the doctor?
You may need to see your doctor regularly while taking Npgab NT 400mg/10mg Tablet. However, if the recommended dosage does not improve your symptoms or you experience unwanted side effects that affect your daily routine, consult your doctor.
Can the use of Npgab NT 400mg/10mg Tablet cause sleepiness or drowsiness?
Yes, Npgab NT 400mg/10mg Tablet may cause drowsiness or sudden episodes of sleepiness. Avoid driving, operating heavy machinery, or participating in potentially dangerous activities until you know how the medication affects you. Inform your doctor if you experience such episodes while taking this medication.
Will Npgab NT 400mg/10mg Tablet be more effective if taken more than recommended dose?
No, taking a higher dose than recommended may not be more effective and may increase the risk of serious side effects and toxicity. If you experience increased severity of symptoms that are not relieved by the recommended doses, consult your doctor for re-evaluation.
What are the storage conditions for Npgab NT 400mg/10mg Tablet?
Store Npgab NT 400mg/10mg Tablet in a cool, dry place, out of sight and out of reach of children. Dispose of unused medications in a special way to ensure they are not consumed by pets, children, or other people.