Noltrexate 5mg Tablet
Manufacturer
Knoll Pharmaceuticals Ltd
Salt Composition
Methotrexate (5mg)
Key Information
Short Description
Noltrexate 5mg Tablet is used for treating various cancers, rheumatoid arthritis, severe psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Noltrexate 5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these. Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Noltrexate 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How it works
Noltrexate 5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division, and leads to anti-inflammatory actions. It kills cancer cells by preventing them from making DNA. It can help control psoriasis by retarding the production of skin cells and suppressing inflammation. It may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to the bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Noltrexate 5mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood tests done to monitor your kidney function, liver function, and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
Related Medicines
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Nidtrex 5mg Tablet
Methora 5 Tablet
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Frequently asked questions
Can Noltrexate 5mg Tablet cause mouth ulcers?
Yes, Noltrexate 5mg Tablet may cause mouth ulcers as a side effect in some cases. Taking folic acid along with this medicine may help reduce the occurrence of ulcers. Your doctor may recommend reducing the dose of Noltrexate 5mg Tablet to minimize the risk of mouth ulcers.
Why do I have to take folic acid with Noltrexate 5mg Tablet?
Folic acid is essential for the production of new cells in the body, and Noltrexate 5mg Tablet can decrease folic acid levels. Folic acid supplementation may help alleviate common side effects of Noltrexate 5mg Tablet, including mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems. Consult your doctor for personalized guidance.
Why do I need to take regular blood tests while taking Noltrexate 5mg Tablet?
Regular blood tests are necessary to monitor your response to Noltrexate 5mg Tablet and detect potential side effects. Your doctor will check your liver function, blood counts (white blood cells, red blood cells, and platelets), and may order additional tests based on the results. It is crucial to follow your doctor's instructions for regular blood tests to ensure safe and effective treatment.
Can Noltrexate 5mg Tablet use make me more prone to infections?
Noltrexate 5mg Tablet may weaken your immune system, increasing the risk of developing serious infections. If you have an active infection, your doctor may recommend using Noltrexate 5mg Tablet with caution. Inform your doctor about any pre-existing infections before starting treatment.
Can Noltrexate 5mg Tablet affect fertility?
Yes, Noltrexate 5mg Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. However, these effects are reversible and typically resolve once treatment is discontinued. Consult your doctor for personalized guidance on fertility concerns.
What to do if I am planning to become pregnant and my husband is taking Noltrexate 5mg Tablet?
It is essential to avoid pregnancy while your husband is taking Noltrexate 5mg Tablet. Additionally, it is recommended to avoid pregnancy for at least 3 months after discontinuing treatment, as it may increase the risk of serious fetal abnormalities. Consult your doctor for personalized guidance on pregnancy planning and Noltrexate 5mg Tablet use.
