Noltrexate 2.5mg Tablet
Manufacturer
Knoll Pharmaceuticals Ltd
Salt Composition
Methotrexate (2.5mg)
Key Information
Short Description
Noltrexate 2.5mg Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Noltrexate 2.5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Noltrexate 2.5mg Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hairloss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Noltrexate 2.5mg Tablet.
Breastfeeding Warning
Noltrexate 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Noltrexate 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Noltrexate 2.5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Noltrexate 2.5mg Tablet kills cancer cells by preventing them from making DNA. Noltrexate 2.5mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Noltrexate 2.5mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Noltrexate 2.5mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
Related Medicines
Folitrax-2.5 Tablet
Mytrexate 2.5mg Tablet
Gerate 2.5mg Tablet
Dermotrex 2.5mg Tablet
Meth 2.5mg Tablet
Methocel 2.5mg Tablet
Glasitrex 2.5mg Tablet
Mecan 2.5 Tablet
Methosis 2.5mg Tablet
Imusis 2.5mg Tablet
Frequently asked questions
Can Noltrexate 2.5mg Tablet cause mouth ulcers?
Yes, Noltrexate 2.5mg Tablet may cause mouth ulcers as a side effect in some cases. Taking folic acid along with this medicine may help reduce the frequency and severity of ulcers. Your doctor may also recommend reducing the dose of Noltrexate 2.5mg Tablet to minimize this side effect.
Why do I have to take folic acid with Noltrexate 2.5mg Tablet?
Folic acid is essential for the production of new cells in the body, and Noltrexate 2.5mg Tablet can decrease folic acid levels. Taking folic acid with Noltrexate 2.5mg Tablet may help alleviate common side effects such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems. However, it is crucial to consult your doctor before taking any medication, including folic acid.
Why do I need to take regular blood tests while taking Noltrexate 2.5mg Tablet?
Regular blood tests are necessary to monitor your response to Noltrexate 2.5mg Tablet and detect any potential side effects. Your doctor will check your liver function, blood counts (white blood cells, red blood cells, and platelets), and may order additional tests based on the results. It is essential to follow your doctor's instructions regarding blood tests to ensure your safety and optimal treatment.
Can Noltrexate 2.5mg Tablet use make me more prone to infections?
Noltrexate 2.5mg Tablet may weaken your immune system, making you more susceptible to infections. In rare cases, serious lung infections have been reported in individuals taking this medication. If you have an active infection, your doctor may recommend caution or alternative treatment options. It is crucial to discuss any concerns or questions with your doctor to ensure safe and effective treatment.
Can Noltrexate 2.5mg Tablet affect fertility?
Yes, Noltrexate 2.5mg Tablet may impact fertility in both males and females. Males may experience a decrease in sperm count, while females may experience menstrual disturbances. However, these effects are typically reversible and may resolve once treatment is discontinued. If you are concerned about fertility or have questions, consult your doctor for personalized guidance.
What to do if I am planning to become pregnant and my husband is taking Noltrexate 2.5mg Tablet?
It is essential to avoid pregnancy while your husband is taking Noltrexate 2.5mg Tablet. Additionally, it is recommended to wait at least 3 months after discontinuing treatment before attempting to conceive, as this medication can increase the risk of serious fetal abnormalities. Consult your doctor for personalized guidance on managing fertility and pregnancy while taking Noltrexate 2.5mg Tablet.
