Nixzide 60mg/500mg Tablet XR
Manufacturer
Nicson Pharma
Salt Composition
Gliclazide (60mg) + Metformin (500mg)
Key Information
Short Description
Nixzide 60mg/500mg Tablet XR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet XR
Introduction
Nixzide 60mg/500mg Tablet XR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nixzide 60mg/500mg Tablet XR is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Nixzide 60mg/500mg Tablet XR.
Breastfeeding Warning
Nixzide 60mg/500mg Tablet XR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Nixzide 60mg/500mg Tablet XR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Nixzide 60mg/500mg Tablet XR is a combination of two antidiabetic medicines: Gliclazide and Metformin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Nixzide 60mg/500mg Tablet XR may cause a rare but serious condition called lactic acidosis.
Related Medicines
Diamicron XR Mex 60/500 Tablet
Vitaglic M XR Tablet
Eldozide XR 60mg/500mg Tablet
Avazide MF 60mg/500mg Tablet XR
Glymade M 60mg/500mg Tablet XR
Mexigliz M 60mg/500mg Tablet XR
Gozide M 60mg/500mg Tablet XR
Loyzide M 60mg/500mg Tablet XR
Loyzide M 60mg/500mg Tablet XR
Frequently asked questions
What is Nixzide 60mg/500mg Tablet XR?
Nixzide 60mg/500mg Tablet XR is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.
What are the possible side effects of Nixzide 60mg/500mg Tablet XR?
The use of Nixzide 60mg/500mg Tablet XR is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
Can the use of Nixzide 60mg/500mg Tablet XR cause hypoglycemia?
Yes, the use of Nixzide 60mg/500mg Tablet XR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.
Can the use of Nixzide 60mg/500mg Tablet XR cause lactic acidosis?
Yes, the use of Nixzide 60mg/500mg Tablet XR can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Nixzide 60mg/500mg Tablet XR and immediately consult your doctor.
Can the use of Nixzide 60mg/500mg Tablet XR lead to Vitamin B12 deficiency?
Yes, the use of Nixzide 60mg/500mg Tablet XR can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
Are there any specific conditions in which Nixzide 60mg/500mg Tablet XR should not to be taken?
The use of Nixzide 60mg/500mg Tablet XR should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.
Is it safe to take alcohol while I am also taking Nixzide 60mg/500mg Tablet XR?
No, it is not safe to take alcohol along with Nixzide 60mg/500mg Tablet XR. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
