Nirglim M 2mg/500mg Tablet
Manufacturer
Nirvana Healthcare
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Nirglim M 2mg/500mg Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
Nirglim M 2mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nirglim M 2mg/500mg Tablet is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Nirglim M 2mg/500mg Tablet.
Breastfeeding Warning
Nirglim M 2mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Nirglim M 2mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Nirglim M 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
You should continue to exercise regularly Eat a healthy diet Take your other diabetes medicines along with Nirglim M 2mg/500mg Tablet. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine.
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Frequently asked questions
What are the recommended storage conditions for Nirglim M 2mg/500mg Tablet?
Store Nirglim M 2mg/500mg Tablet in its original container, tightly closed, and according to the instructions provided on the packaging or label. Dispose of any unused medication and ensure it is not accessible to pets, children, or other individuals.
Can the use of Nirglim M 2mg/500mg Tablet lead to lactic acidosis?
Yes, the use of Nirglim M 2mg/500mg Tablet can lead to lactic acidosis, a medical emergency characterized by elevated blood lactic acid levels. This rare side effect is more likely to occur in patients with underlying kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms may include muscle pain or weakness, dizziness, fatigue, cold extremities, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, discontinue use and consult your doctor immediately.
What is Nirglim M 2mg/500mg Tablet?
Nirglim M 2mg/500mg Tablet is a combination medication containing Glimepiride and Metformin. It is used to treat type 2 diabetes mellitus (DM) in adults, improving blood glucose levels when taken with a proper diet and regular exercise. Glimepiride increases insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Nirglim M 2mg/500mg Tablet?
Common side effects of Nirglim M 2mg/500mg Tablet include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may include lactic acidosis. Long-term use can also lead to Vitamin B12 deficiency, which may cause anemia, nerve problems, and symptoms such as tingling sensations, numbness, weakness, urinary issues, changes in mental status, and balance difficulties.
Can the use of Nirglim M 2mg/500mg Tablet lead to Vitamin B12 deficiency?
Yes, the use of Nirglim M 2mg/500mg Tablet can cause Vitamin B12 deficiency on long-term use, as it interferes with stomach absorption. Untreated deficiency may lead to anemia, nerve problems, and symptoms such as tingling sensations, numbness, weakness, urinary issues, changes in mental status, and balance difficulties. To avoid these issues, consider taking Vitamin B12 supplements at least once a year.
Can the use of Nirglim M 2mg/500mg Tablet cause hypoglycemia?
Yes, Nirglim M 2mg/500mg Tablet can cause hypoglycemia (low blood sugar). Symptoms may include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feelings of anxiety or shakiness. This is more likely to occur if you miss or delay meals, consume alcohol, over-exercise, or take other antidiabetic medications. Regular blood sugar monitoring is essential, and it is recommended to keep a quick source of sugar, such as glucose tablets, honey, or fruit juice, readily available.
Is it safe to take alcohol while I am also taking Nirglim M 2mg/500mg Tablet?
No, it is not recommended to consume alcohol while taking Nirglim M 2mg/500mg Tablet, as it may lower blood sugar levels and increase the risk of hypoglycemia and lactic acidosis.
