
Nidtrex 5mg Tablet
Manufacturer
Nidus Pharma Pvt Ltd
Salt Composition
Methotrexate (5mg)
Key Information
Short Description
Nidtrex 5mg Tablet is a medicine used for treatment of cancer in various parts of the body, rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn's disease.
Dosage Form
Tablet
Introduction
Nidtrex 5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nidtrex 5mg Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hair loss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Nidtrex 5mg Tablet.
Breastfeeding Warning
Nidtrex 5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Nidtrex 5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Nidtrex 5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Nidtrex 5mg Tablet kills cancer cells by preventing them from making DNA. Nidtrex 5mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Nidtrex 5mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Nidtrex 5mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Frequently asked questions
Can Nidtrex 5mg Tablet cause mouth ulcers?
Yes, Nidtrex 5mg Tablet can cause oral discomfort and ulcers as a side effect in some individuals. Combining folic acid with this medication may help alleviate these ulcers. Consult your doctor about potential dose reduction to further reduce the likelihood of ulcers.
Why do I need to take folic acid along with Nidtrex 5mg Tablet?
Folic acid plays a vital role in cell creation within the body, and Nidtrex 5mg Tablet can deplete folic acid levels. Folic acid supplementation may help mitigate some common side effects of Nidtrex 5mg Tablet, including mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why do I need regular blood tests while taking Nidtrex 5mg Tablet?
Regular blood tests are crucial for monitoring your response to Nidtrex 5mg Tablet and assessing potential side effects. These tests will evaluate liver function and blood counts (white blood cells, red blood cells, and platelets). Your doctor may prescribe additional testing based on the initial test results.
Can Nidtrex 5mg Tablet increase my susceptibility to infections?
Nidtrex 5mg Tablet might weaken your immune system. Consequently, you could become more susceptible to serious infections. There have been reports of severe lung infections associated with Nidtrex 5mg Tablet use. In case of an active infection, this medication should be used with extreme caution.
Can Nidtrex 5mg Tablet affect my fertility?
Yes, Nidtrex 5mg Tablet can impact both male and female fertility. It may decrease sperm count in men and trigger menstrual irregularities in women. Importantly, these effects are reversible and disappear upon discontinuation of the medication.
What should I do if I am planning to become pregnant while my husband is on Nidtrex 5mg Tablet?
Pregnant or potentially pregnant individuals seeking to conceive should avoid using Nidtrex 5mg Tablet until a minimum of three months after the end of treatment. This medication can pose risks for fetal abnormalities.