Neuzumab 440mg Injection
Manufacturer
Lupin Ltd
Salt Composition
Trastuzumab (440mg)
Key Information
Short Description
Neuzumab 440mg Injection is used to treat breast and stomach cancer by killing cancer cells by inhibiting HER2 protein.
Dosage Form
Injection
Introduction
Neuzumab 440mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How it works
Neuzumab 440mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.
Quick Tips
It is given as an injection into your vein or under the skin usually over 1 hour Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment. Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shivering, swelling of legs and arm. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Frequently asked questions
What are the serious side effects of Neuzumab 440mg Injection?
Neuzumab 440mg Injection may cause various side effects, including sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. Additionally, patients may experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Other possible side effects include nausea or vomiting, loss of appetite, fatigue, rapid heartbeat, discoloration of urine, decreased amount of urine, difficulty urinating, pain when urinating, and signs of infection. If you experience any of these symptoms, it is essential to consult your doctor immediately.
How long after Neuzumab 440mg Injection therapy can I get pregnant?
Women of child-bearing age should use effective contraception during Neuzumab 440mg Injection therapy and for 7 months after completing the treatment. It is recommended to plan your pregnancy after 7 months of treatment with Neuzumab 440mg Injection.
How long should Neuzumab 440mg Injection be taken?
Patients with early breast cancer should take Neuzumab 440mg Injection for 1 year or until disease recurs, whichever occurs first. It is not recommended to extend the treatment beyond 1 year in patients with early breast cancer.
Is fasting required before administering Neuzumab 440mg Injection?
No, fasting is not required before administering Neuzumab 440mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.
How is Neuzumab 440mg Injection given, intravenously or intramuscularly?
Neuzumab 440mg Injection is available in two formulations: an infusion into a vein (intravenous infusion) and an injection under the skin (subcutaneous injection). It is essential to check the product labels to ensure that the correct formulation is being given as prescribed. The intravenous formulation should only be given as an intravenous infusion, and the subcutaneous formulation should only be given as an injection under the skin. Your doctor may consider switching your treatment from one formulation to another if deemed appropriate for you.
Can Neuzumab 440mg Injection be given to HER2 negative cancer patients?
No, Neuzumab 440mg Injection is not suitable for patients with HER2 negative cancer cells. It is a monoclonal antibody that binds selectively to the human epidermal growth factor receptor 2 (HER2) protein, which is present on the surface of some cancer cells. Therefore, it is only effective in HER2 positive patients and will not be beneficial for HER2 negative patients.
Why has my doctor advised for investigations of heart?
Neuzumab 440mg Injection, when used with anthracycline class of anti-cancer medicines, may have adverse effects on the heart. Therefore, your doctor needs to check the health of your heart initially before starting treatment and during treatment.
How frequently heart investigations are required?
Heart investigations should be performed at the start of treatment, every 3 months during treatment, and every 6 months after discontinuation of treatment until 24 months from the last administration of Neuzumab 440mg Injection. Patients with pre-existing heart-related problems will require investigations every 12 weeks.
