Mtxe 15 Tablet
Manufacturer
Ankaa Pharmaceutical
Salt Composition
Methotrexate (15mg)
Key Information
Short Description
Mtxe 15 Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Mtxe 15 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mtxe 15 Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Mtxe 15 Tablet.
Breastfeeding Warning
Mtxe 15 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Mtxe 15 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Mtxe 15 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Mtxe 15 Tablet kills cancer cells by preventing them from making DNA. Mtxe 15 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Mtxe 15 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Mtxe 15 Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Methora 15 Tablet
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Frequently asked questions
Can Mtxe 15 Tablet cause mouth ulcers?
Yes, Mtxe 15 Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers.
Why do I need to take folic acid with Mtxe 15 Tablet?
Folic acid is required to make new cells in the body and Mtxe 15 Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Mtxe 15 Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.
Why do I need to take regular blood tests while taking Mtxe 15 Tablet?
Regular blood tests will help your doctor to check your response to Mtxe 15 Tablet and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells, and platelets). Your doctor may also order additional tests depending on the results.
Can Mtxe 15 Tablet make me more prone to infections?
Mtxe 15 Tablet may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Mtxe 15 Tablet use. If you have an active infection, Mtxe 15 Tablet should be used with extreme caution.
Can Mtxe 15 Tablet affect fertility?
Yes, Mtxe 15 Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.
What should I do if I am planning to become pregnant and my husband is taking Mtxe 15 Tablet?
You should avoid pregnancy if your husband is taking Mtxe 15 Tablet. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
