

Mtxe 10 Tablet
Manufacturer
Ankaa Pharmaceutical
Salt Composition
Methotrexate (10mg)
Key Information
Short Description
Mtxe 10 Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Mtxe 10 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mtxe 10 Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hairloss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Mtxe 10 Tablet.
Breastfeeding Warning
Mtxe 10 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Mtxe 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Mtxe 10 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Mtxe 10 Tablet kills cancer cells by preventing them from making DNA. Mtxe 10 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Mtxe 10 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Mtxe 10 Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Frequently asked questions
Does Mtxe 10 Tablet cause mouth ulcers?
Yes, some people taking Mtxe 10 Tablet may experience a sore mouth and develop mouth ulcers. Combining Mtxe 10 Tablet with folic acid might help reduce the likelihood of these side effects.
Why do I need to take folic acid along with Mtxe 10 Tablet?
Folic acid is essential for making new cells in the body, and Mtxe 10 Tablet can lower the amount of folic acid you have. This combination may help reduce side effects like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why do I need to take regular blood tests while taking Mtxe 10 Tablet?
Regular blood tests help your doctor understand how your body is responding to Mtxe 10 Tablet. These tests will monitor your liver function, red blood cell counts, white blood cell counts, and platelet counts. Your doctor may recommend further testing based on these results.
Can Mtxe 10 Tablet make me more prone to infections?
Mtxe 10 Tablet might lower your immune system activity, increasing the risk of serious infections. Rare cases have reported severe lung infections associated with Mtxe 10 Tablet use. If you already have an active infection, it is crucial to be very cautious when taking Mtxe 10 Tablet.
Can Mtxe 10 Tablet affect fertility?
Yes, Mtxe 10 Tablet may affect both male and female fertility. It can lead to decreased sperm count in men and menstrual irregularities in women. It's important to note that these effects are reversible, and they will disappear once you stop taking the medication.
What should I do if I plan to get pregnant while my husband is on Mtxe 10 Tablet?
If you and your partner both are planning a pregnancy, it's crucial to consider avoiding it until at least 3 months after stopping the treatment. This is because the medication may lead to serious fetal abnormalities.