Mexate 10 Tablet
Manufacturer
Zydus Cadila
Salt Composition
Methotrexate (10mg)
Key Information
Short Description
Mexate 10 Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Mexate 10 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mexate 10 Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hairloss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Mexate 10 Tablet.
Breastfeeding Warning
Mexate 10 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Mexate 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Mexate 10 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Mexate 10 Tablet kills cancer cells by preventing them from making DNA. Mexate 10 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Mexate 10 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Mexate 10 Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
Related Medicines
Folitrax-10 Tablet
Noltrexate 10mg Tablet
Arthrate 10mg Tablet
Aariv 10mg Tablet
Methate 10mg Tablet
Prestrex 10mg Tablet
Trexomune 10 Tablet
Dermatrax 10mg Tablet
Meritrax Tablet
Mext 10 Tablet
Frequently asked questions
Can Mexate 10 Tablet cause mouth ulcers?
Yes, Mexate 10 Tablet may cause sore mouths and mouth ulcers as side effects in some individuals. Taking folic acid alongside this medication may help reduce the occurrence of ulcers. It is advised to consult your doctor regarding potential dose adjustments, as reducing the dosage may further aid in ulcer reduction.
Why am I required to take folic acid with Mexate 10 Tablet?
Folic acid plays a vital role in cell creation within the body, and Mexate 10 Tablet decreases folic acid levels. This medication may help reduce side effects of Mexate 10 Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems by increasing cellular activity.
Why do I need regular blood tests while taking Mexate 10 Tablet?
Regular blood tests are essential to monitor your response to Mexate 10 Tablet and help identify any potential side effects. These tests assess liver function and blood cell counts (white blood cells, red blood cells, and platelets). The frequency of these tests may vary based on individual responses.
Can Mexate 10 Tablet make me more susceptible to infections?
Mexate 10 Tablet might weaken your immune system, increasing the risk of serious infections. There are rare reports of severe lung infections associated with Mexate 10 Tablet use. If you have an active infection, using Mexate 10 Tablet should be strictly avoided.
Can Mexate 10 Tablet affect fertility?
Yes, Mexate 10 Tablet may impact fertility in both males and females. It can potentially decrease sperm count in men and trigger menstrual irregularities in women. These effects are usually reversible upon discontinuing treatment.
What should I do if I am planning to become pregnant while my husband is taking Mexate 10 Tablet?
It is advisable to abstain from pregnancy until your husband has stopped taking Mexate 10 Tablet. It's recommended that pregnancy be avoided for at least three months after the medication's discontinuation, as this period may lead to potential fetal abnormalities.
