Metraff-G1 Tablet SR
Manufacturer
Raffles Pharmaceuticals
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Metraff-G1 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Metraff-G1 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metraff-G1 Tablet SR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Metraff-G1 Tablet SR may cause a rare but serious condition called lactic acidosis
Alcohol Warning
It is unsafe to consume alcohol with Metraff-G1 Tablet SR.
Breastfeeding Warning
Metraff-G1 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Metraff-G1 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Metraff-G1 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Metraff-G1 Tablet SR may cause a rare but serious condition called lactic acidosis
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Frequently asked questions
What are the recommended storage conditions for Metraff-G1 Tablet SR?
Keep this medicine in its original container or pack, tightly closed. Store it according to the instructions on the label. Dispose of unused medication and ensure pets, children, and others do not consume it.
Can Metraff-G1 Tablet SR lead to lactic acidosis?
Yes, Metraff-G1 Tablet SR can lead to lactic acidosis. It is a medical emergency caused by increased levels of lactic acid in the blood and is known as MALA (Metformin-associated lactic acidosis). This is a rare side effect associated with metformin use and can be harmful for patients with pre-existing kidney disease, elderly individuals, or those who regularly consume alcohol in large amounts. Symptoms include muscle pain or weakness, dizziness, fatigue, coldness in the arms and legs, difficulty breathing, nausea, vomiting, stomach pain, and a slow heart rate. If you experience these symptoms, discontinue Metraff-G1 Tablet SR immediately and consult your doctor.
What is Metraff-G1 Tablet SR?
Metraff-G1 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used for the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken alongside proper diet and exercise. Glimepiride lowers blood glucose levels by increasing insulin release from the pancreas. Metformin works by reducing glucose production in the liver and enhancing insulin sensitivity. This combination is not indicated for treating type 1 DM.
What are the possible side effects of Metraff-G1 Tablet SR?
The use of Metraff-G1 Tablet SR may lead to common side effects such as hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headaches. It can also cause serious but rare side effects, like lactic acidosis. In the long term, it can lead to vitamin B12 deficiency.
Can the use of Metraff-G1 Tablet SR lead to Vitamin B12 deficiency?
Yes, the use of Metraff-G1 Tablet SR can contribute to vitamin B12 deficiency over time. It interferes with vitamin B12 absorption in the stomach. If not addressed, this can lead to anemia and nerve problems, causing tingling sensations in the hands and feet, weakness, urinary issues, changes in mental status, and difficulty maintaining balance (ataxia). To avoid such complications, it's recommended to consume Vitamin B12 from external sources at least once a year.
Can the use of Metraff-G1 Tablet SR cause hypoglycemia?
Yes, using Metraff-G1 Tablet SR can lead to hypoglycemia (low blood sugar levels). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It is more likely to occur if you miss meals, drink alcohol, over-exercise, take other antidiabetic medications with it, or delay your eating schedule.
Is it safe to take alcohol while taking Metraff-G1 Tablet SR?
No, it is not safe to combine alcohol with Metraff-G1 Tablet SR. Alcohol can lower blood sugar levels and increase the risk of hypoglycemia. It also increases the likelihood of lactic acidosis.
