
Metoliz G 2mg/500mg Tablet SR
Manufacturer
Crinova Healthcare
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Metoliz G 2mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Metoliz G 2mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metoliz G 2mg/500mg Tablet SR is to be taken with food.
How it works
Metoliz G 2mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting and stomach pain as Metoliz G 2mg/500mg Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Metoliz G 2mg/500mg Tablet SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Can the use of Metoliz G 2mg/500mg Tablet SR lead to lactic acidosis?
Yes, the use of Metoliz G 2mg/500mg Tablet SR can lead to lactic acidosis. It is a medical emergency caused by increased levels of lactic acid in the blood. This is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with metformin and therefore, it is considered harmful for patients with underlying kidney disease, old age patients, or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, stop taking Metoliz G 2mg/500mg Tablet SR and consult your doctor immediately.
What is Metoliz G 2mg/500mg Tablet SR?
Metoliz G 2mg/500mg Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose level by increasing insulin release from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Metoliz G 2mg/500mg Tablet SR?
The use of Metoliz G 2mg/500mg Tablet SR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its long-term use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also cause Vitamin B12 deficiency.
Can the use of Metoliz G 2mg/500mg Tablet SR lead to Vitamin B12 deficiency?
Yes, the use of Metoliz G 2mg/500mg Tablet SR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems; the patient might experience tingling sensation and numbness in hands and feet, weakness, urinary problems, a change in mental status, and difficulty maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
Can the use of Metoliz G 2mg/500mg Tablet SR cause hypoglycemia?
Yes, the use of Metoliz G 2mg/500mg Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey, or fruit juice with you.
Is it safe to take alcohol while I am also taking Metoliz G 2mg/500mg Tablet SR?
No, it is not safe to take Metoliz G 2mg/500mg Tablet SR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.