
Meglisil 1mg/500mg Tablet SR
Manufacturer
Silicon Pharma
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Meglisil 1mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Meglisil 1mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meglisil 1mg/500mg Tablet SR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Meglisil 1mg/500mg Tablet SR may cause a rare but serious condition called lactic acidosis
Alcohol Warning
It is unsafe to consume alcohol with Meglisil 1mg/500mg Tablet SR.
Breastfeeding Warning
Meglisil 1mg/500mg Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Meglisil 1mg/500mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Meglisil 1mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Related Medicines

Isryl-M 1 Tablet

Glyconorm G 1mg/500mg Tablet SR

Giomed M 1mg/500mg Tablet SR

Glimscan-M 1 Tablet SR

Opglim M 1mg/500mg Tablet SR

Met-G1 Tablet SR

Glimiclan M 1mg/500mg Tablet SR

Diaset M 1 SR Tablet

Setglim M 1mg/500mg Tablet SR

Oglim G 1mg/500mg Tablet SR
Frequently asked questions
What are the recommended storage conditions for Meglisil 1mg/500mg Tablet SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can Meglisil 1mg/500mg Tablet SR cause lactic acidosis?
Yes, using Meglisil 1mg/500mg Tablet SR can cause lactic acidosis. It is a rare but serious side effect that occurs when there are excessive levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). This is mainly linked to the use of metformin, and therefore it is considered harmful for patients with underlying kidney disease, older adults, or those taking large amounts of alcohol. If you suspect lactic acidosis, immediately stop using Meglisil 1mg/500mg Tablet SR and consult your doctor.
What is Meglisil 1mg/500mg Tablet SR?
Meglisil 1mg/500mg Tablet SR is a combination of two medications: Glimepiride and Metformin. This medicine is used to treat type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride reduces blood glucose by increasing insulin release from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. Meglisil 1mg/500mg Tablet SR is not indicated for the treatment of type 1 diabetes.
What are the possible side effects of Meglisil 1mg/500mg Tablet SR?
Side effects of using Meglisil 1mg/500mg Tablet SR may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. It can also lead to serious but rare side effects like lactic acidosis. Over time, long-term use may also cause Vitamin B12 deficiency.
Can Meglisil 1mg/500mg Tablet SR cause vitamin B12 deficiency?
Yes, the use of Meglisil 1mg/500mg Tablet SR can lead to vitamin B12 deficiency on long-term use. It interferes with Vitamin B12 absorption in the stomach. If not treated, this may result in anemia and nerve problems. These symptoms include tingling sensations and numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty maintaining balance (ataxia). To avoid such issues, consider taking vitamin B12 supplements regularly.
Can Meglisil 1mg/500mg Tablet SR cause hypoglycemia?
Yes, Meglisil 1mg/500mg Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It is more likely to occur if you miss meals, drink alcohol, over-exercise, or take other antidiabetic medications alongside it. Regular monitoring of blood sugar levels is important. Have a quick source of sugar, like glucose tablets, honey, or fruit juice, with you at all times.
Is it safe to drink alcohol while taking Meglisil 1mg/500mg Tablet SR?
No, it is not safe to drink alcohol while using Meglisil 1mg/500mg Tablet SR. Alcohol may lower your blood sugar levels and increase the risk of lactic acidosis.