

Matibenz 100 Capsule
Manufacturer
Admac Pharma Ltd
Salt Composition
Imatinib mesylate (100mg)
Key Information
Short Description
Matibenz 100 Capsule is used to treat several types of cancers, including blood cancers and gastrointestinal stromal tumors.
Dosage Form
Capsule
Introduction
Matibenz 100 Capsule is an anti-cancer medication that works by targeting specific proteins that contribute to the growth and spread of cancer cells. It is most commonly prescribed to treat blood cancers (chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors. The medicine should be taken with food. Take it at the same time each day to get the most benefit. Continue taking it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Matibenz 100 Capsule is to be taken with food.
Safety Information
Side Effects
Edema Nausea Vomiting Muscle cramps Musculoskeletal pain Diarrhea Rash Fatigue Abdominal pain
Alcohol Warning
It is not known whether it is safe to consume alcohol with Matibenz 100 Capsule. Please consult your doctor.
Breastfeeding Warning
Matibenz 100 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Lactating women should not breastfeed while using this drug and 15 days after stopping it.
Pregnancy Warning
Matibenz 100 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Interacting Medicines
Atorvastatin Carbamazepine Fluvastatin Lovastatin
How it works
Matibenz 100 Capsule is an anti-cancer medication. A protein enzyme bcr-abl tyrosine kinase responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.
Quick Tips
Always take it with food and a full glass of water to prevent nausea. It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you. Water retention and swelling are very common side effects of Matibenz 100 Capsule. Notify your doctor if you have unexpected rapid weight gain. Do not change the dose or discontinue use without consulting your doctor. Notify your doctor about all the medications you are taking including over the counter medicines and dietary supplements.
Related Medicines

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Imanex 100mg Capsule

Imanib 100mg Capsule

Resimat 100mg Capsule

Chemotinib 100mg Capsule
Frequently asked questions
Can Matibenz 100 Capsule be taken with food?
Yes, the best way to take it is with a glass of water and food. This prevents irritation in the food pipe and stomach. If you cannot swallow it, put the tablets in a glass of water or apple juice (approximately 50 ml for a 100 mg tablet and 200 ml for a 400 mg tablet). Stir it with a spoon to make it uniform and drink it immediately.
Is it safe to drive while taking Matibenz 100 Capsule?
Matibenz 100 Capsule may cause dizziness, lightheadedness or drowsiness in some people. Make sure you know how you react to it before you drive a car or operate machinery.
What precautions need to be followed while taking Matibenz 100 Capsule?
While taking Matibenz 100 Capsule, make sure you follow all the instructions given by your doctor carefully and keep all appointments. You will need regular follow-up to ensure that the treatment is working. Regular blood tests, weight checks, and urine tests may be required to find out any side effects before it becomes serious. Make sure you use a method of contraception to prevent pregnancy during treatment with Matibenz 100 Capsule. Tell your doctor immediately if you become pregnant while you are taking this medicine. If you are about to start taking any new medicine, remind your doctor that you are taking Matibenz 100 Capsule.
Ever since I started using Matibenz 100 Capsule, I have noticed that I develop rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?
This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness or severe sunburn. When you are outdoors, wear protective clothing and use a sunscreen with an SPF of 15 or higher. If you feel a burning sensation on your skin, tell your doctor.
The doctor has advised me not to take any medicine on my own while taking Matibenz 100 Capsule. Should I consult my doctor even if I need to take paracetamol for my fever?
Yes, there are a number of medicines which interfere with Matibenz 100 Capsule, including paracetamol. Therefore you should not self medicate while taking Matibenz 100 Capsule. Other medicines which interfere with Matibenz 100 Capsule include cyclosporin, dexamethasone (a steroid), warfarin, antiviral medicines which treat AIDS and some medicines which treat bacterial infections, high cholesterol, high blood pressure, heart problems, and mental disorders and depression. Consult your doctor before taking any medicine, and inform him that you are on Matibenz 100 Capsule therapy.
Can I expect that if I take Matibenz 100 Capsule regularly and as advised by the doctor for CML, I will be cured?
Matibenz 100 Capsule has been shown to be effective in many cases of CML. The chances of survival increase after taking this medicine. Your doctor can give you a better answer based on your specific condition and treatment plan. It's important to have open communication with your doctor during the course of your therapy.