Marknase MF 5mg/500mg Tablet
Manufacturer
Elixir Life Care Pvt Ltd
Salt Composition
Glipizide (5mg) + Metformin (00mg)
Key Information
Short Description
Marknase MF 5mg/500mg Tablet is an anti-diabetic drug used to treat type 2 diabetes mellitus in adults by controlling blood sugar levels.
Dosage Form
Tablet
Introduction
Marknase MF 5mg/500mg Tablet is a combination of two antidiabetic medicines: Glipizide and Metformin. It should be taken with food and at the same time each day for maximum benefit. Regular monitoring of blood sugar levels is essential. Common side effects include hypoglycemia, taste changes, nausea, diarrhea, stomach pain, headache, edema, blurred vision, bone fracture, and upper respiratory tract infection. It is not suitable for type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disease. Pregnant or breastfeeding women should consult their doctor before use.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Marknase MF 5mg/500mg Tablet is to be taken with food.
How it works
Marknase MF 5mg/500mg Tablet is a combination of two antidiabetic medicines: Glipizide and Metformin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as it may cause lactic acidosis. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
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Frequently asked questions
What is Marknase MF 5mg/500mg Tablet?
Marknase MF 5mg/500mg Tablet is a combination of Glipizide and Metformin, used to treat type 2 diabetes mellitus (DM). It works by improving blood glucose levels in adults when combined with proper diet and exercise. Glipizide increases insulin release from the pancreas, while metformin reduces glucose production in the liver and improves insulin sensitivity.
What are the possible side effects of Marknase MF 5mg/500mg Tablet?
Possible side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Long-term use can lead to Vitamin B12 deficiency.
Can the use of Marknase MF 5mg/500mg Tablet cause hypoglycemia?
Yes, Marknase MF 5mg/500mg Tablet can cause hypoglycemia (low blood sugar). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It is more likely to occur if you miss meals, drink alcohol, over-exercise, or take other antidiabetic medications concurrently.
Can the use of Marknase MF 5mg/500mg Tablet cause lactic acidosis?
Yes, it can. Lactic acidosis is a medical emergency caused by an increase in blood lactate levels. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect of metformin, therefore it should be avoided in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms may include muscle pain, dizziness, tiredness, cold extremities, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate.
Can the use of Marknase MF 5mg/500mg Tablet lead to Vitamin B12 deficiency?
Yes, long-term use can cause Vitamin B12 deficiency. This is because the medication interferes with vitamin B12 absorption in the stomach. Untreated, it can cause anemia and nerve problems and symptoms may include tingling sensations and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To avoid these problems, consider regular intake of Vitamin B12 supplements.
Are there any specific conditions in which Marknase MF 5mg/500mg Tablet should not be taken?
It is important to avoid taking this medication if you have allergies to the components or excipients of the medicine. It should also be avoided in patients with moderate to severe kidney disease and underlying metabolic acidosis, including diabetic ketoacidosis.
Is it safe to take alcohol while I am also taking Marknase MF 5mg/500mg Tablet?
No, mixing alcohol with Marknase MF 5mg/500mg Tablet is not advised as it can lower blood sugar (hypoglycemia) and increase the risk of lactic acidosis.
What are the instructions for storage and disposal of Marknase MF 5mg/500mg Tablet?
Keep this medicine in its original container or package, tightly closed. Store it as indicated on the label. Never dispose of unused medication down the drain or allow pets, children, or others to access it.
