Lukster 50mg Injection
Manufacturer
Metta Life Sciences Private Limited
Salt Composition
Calcium Leucovorin (50mg)
Key Information
Short Description
Lukster 50mg Injection is used to prevent the harmful effects of methotrexate (anticancer medicine) and to treat overdose of methotrexate.
Dosage Form
Injection
Introduction
Lukster 50mg Injection is given as a slow injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. Injection site reactions (pain, swelling, redness) are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in blood. Before taking it, tell your doctor if you have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To make sure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How it works
Lukster 50mg Injection is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.
Quick Tips
You have been prescribed Lukster 50mg Injection to reduce the side effects of the medicine methotrexate. Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate. Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Lukster 50mg Injection may counteract the antiepileptic effects.
Frequently asked questions
What is Lukster 50mg Injection used for?
Lukster 50mg Injection is used to prevent harm from methotrexate when it's used to treat certain types of cancer. It's also used to treat people who have taken too much methotrexate or similar medications by accident. Additionally, Lukster 50mg Injection treats megaloblastic anemia caused by a lack of folic acid and is given when oral treatment isn't possible.
What is megaloblastic anemia?
Megaloblastic anemia is a type of anemia where the red blood cells are larger than usual, and there's not enough of them. This condition usually happens because of a lack of vitamin B12 or folic acid.
How long does it take for Lukster 50mg Injection to work?
Lukster 50mg Injection starts working within 5 minutes after administration, but this can vary depending on the dose, patient, and treatment response.
What laboratory tests are conducted before or during treatment with Lukster 50mg Injection?
Blood tests will be prescribed to check your serum methotrexate concentration if you're receiving methotrexate chemotherapy or have taken too much. A complete blood count will also be done to monitor the number of red blood cells, and calcium levels will be checked to prevent hypercalcemia since Lukster 50mg Injection contains calcium.
What measures should be taken to ensure prompt excretion of methotrexate during treatment with Lukster 50mg Injection?
To help methotrexate leave your body quickly, you'll need to produce at least 2,500 mL of urine in a 24-hour period by drinking more fluids. Your doctor may also ask you to avoid foods and drinks that can make your urine acidic and to keep an eye on the pH level of your urine to ensure it's above 7.0 before starting methotrexate treatment.
