Locomet G 0.5mg/500mg Tablet SR
Manufacturer
Locus Pharma Pvt Ltd
Salt Composition
Glimepiride (0.5mg) + Metformin (500mg)
Key Information
Short Description
Locomet G 0.5mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Locomet G 0.5mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Locomet G 0.5mg/500mg Tablet SR is to be taken with food.
How it works
Locomet G 0.5mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting and stomach pain as Locomet G 0.5mg/500mg Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Locomet G 0.5mg/500mg Tablet SR?
For optimal efficacy, store this medicine in its original container or pack, tightly closed, according to the instructions on the label or packaging. Dispose of any unused medication properly, and ensure it is out of reach of children, pets, and other individuals.
Can the use of Locomet G 0.5mg/500mg Tablet SR lead to lactic acidosis?
Yes, lactic acidosis, a serious medical condition caused by elevated blood lactate levels, can occur with the use of Locomet G 0.5mg/500mg Tablet SR. This rare side effect is more likely in patients with underlying kidney disease, elderly individuals, or those consuming large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, tiredness, feeling cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, discontinue the medication and consult your doctor immediately.
What is Locomet G 0.5mg/500mg Tablet SR?
Locomet G 0.5mg/500mg Tablet SR is a combination of Glimepiride and Metformin, used to treat type 2 diabetes mellitus (DM) in adults. This medication improves blood glucose levels when taken with a balanced diet and regular exercise. Glimepiride works by increasing insulin release from the pancreas, while Metformin lowers glucose production in the liver and enhances insulin sensitivity. It is not intended for treating type 1 DM.
What are the possible side effects of Locomet G 0.5mg/500mg Tablet SR?
Common side effects associated with Locomet G 0.5mg/500mg Tablet SR include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may occur, such as lactic acidosis or Vitamin B12 deficiency on long-term use. If untreated, Vitamin B12 deficiency can cause anemia, nerve problems, tingling sensation in hands and feet, weakness, urinary issues, changes in mental status, and difficulty maintaining balance.
Can the use of Locomet G 0.5mg/500mg Tablet SR lead to Vitamin B12 deficiency?
Yes, prolonged use of Locomet G 0.5mg/500mg Tablet SR can cause Vitamin B12 deficiency due to interference with stomach absorption. Untreated Vitamin B12 deficiency may result in anemia and nerve problems, leading to symptoms like tingling sensation in hands and feet, weakness, urinary issues, changes in mental status, and difficulty maintaining balance. Regular monitoring and supplementation are recommended.
Can the use of Locomet G 0.5mg/500mg Tablet SR cause hypoglycemia?
Yes, Locomet G 0.5mg/500mg Tablet SR can lead to hypoglycemia (low blood sugar), especially when taken with inadequate food, excessive exercise, or other antidiabetic medications. Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Regular blood sugar monitoring is essential to prevent and manage hypoglycemic episodes.
Is it safe to take alcohol while I am also taking Locomet G 0.5mg/500mg Tablet SR?
No, consuming alcohol while on Locomet G 0.5mg/500mg Tablet SR can lower blood sugar levels and increase the risk of lactic acidosis. It is essential to avoid mixing these substances to ensure safe and effective medication use.
