Leetrexate 15mg Tablet
Manufacturer
Johnlee Pharmaceuticals Pvt Ltd
Salt Composition
Methotrexate (15mg)
Key Information
Short Description
Leetrexate 15mg Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Dosage Form
Tablet
Introduction
Leetrexate 15mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leetrexate 15mg Tablet may be taken with or without food but it is better to take it at a fixed time.
Safety Information
Side Effects
ulcerative stomatitis hairloss low blood cell count increased liver enzymes nausea abdominal distress
Alcohol Warning
It is unsafe to consume alcohol with Leetrexate 15mg Tablet.
Breastfeeding Warning
Leetrexate 15mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Leetrexate 15mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Interacting Medicines
Rotavirus vaccine (live attenuated, oral) Live Attenuated Varicella-Zoster Virus Measles Vaccine (Live) Rubella vaccine (Live)
How it works
Leetrexate 15mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Leetrexate 15mg Tablet kills cancer cells by preventing them from making DNA. Leetrexate 15mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Leetrexate 15mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Leetrexate 15mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Frequently asked questions
Can Leetrexate 15mg Tablet cause mouth ulcers?
Yes, Leetrexate 15mg Tablet may cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medication may help to reduce the ulcers. It is important to discuss dose adjustments with your doctor if necessary.
Why do I need to take folic acid with Leetrexate 15mg Tablet?
Folic acid is essential for making new cells in the body, and Leetrexate 15mg Tablet can decrease folic acid levels. Folic acid may help reduce some of the common side effects of Leetrexate 15mg Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why do I need to take regular blood tests while taking Leetrexate 15mg Tablet?
Regular blood tests will help your doctor assess your response to Leetrexate 15mg Tablet and monitor you for side effects. Your blood count (white blood cells, red blood cells, and platelets), liver function, and other relevant factors will be checked during these tests. Your doctor may also order additional tests based on the initial results.
Can Leetrexate 15mg Tablet increase susceptibility to infections?
Leetrexate 15mg Tablet can decrease your immune system's activity, potentially increasing your risk of developing serious infections. There have been rare reports indicating a link between Leetrexate 15mg Tablet and severe lung infections. It is crucial to use this medication with extreme caution if you have an active infection.
Can Leetrexate 15mg Tablet affect fertility?
Yes, Leetrexate 15mg Tablet may negatively impact both male and female fertility. It can cause a decrease in sperm count in men and menstrual irregularities in women. It's important to note that these effects are typically reversible after discontinuing the medication.
What should I do if I plan to become pregnant while my husband is taking Leetrexate 15mg Tablet?
Avoid getting pregnant if your husband is on Leetrexate 15mg Tablet. It's also recommended to avoid pregnancy for at least three months after the therapy, as it may lead to serious fetal abnormalities.
