Kombiglyze XR 5mg/500mg Tablet
Manufacturer
AstraZeneca
Salt Composition
Saxagliptin (5mg) + Metformin (500mg)
Key Information
Short Description
Kombiglyze XR 5mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus.
Dosage Form
Tablet XR
Introduction
Kombiglyze XR 5mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kombiglyze XR 5mg/500mg Tablet is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Kombiglyze XR 5mg/500mg Tablet.
Breastfeeding Warning
Kombiglyze XR 5mg/500mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Kombiglyze XR 5mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Kombiglyze XR 5mg/500mg Tablet is a combination of two antidiabetic medicines:
Quick Tips
Take it with food to lower your chance of having an upset stomach. Chances of low blood sugar are lesser as compared to other diabetes medicines. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Kombiglyze XR 5mg/500mg Tablet may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
Frequently asked questions
What should I tell my doctor before taking Kombiglyze XR 5mg/500mg Tablet?
Before taking Kombiglyze XR 5mg/500mg Tablet, inform your doctor about any pre-existing medical conditions, including kidney, liver, bladder, heart, or pancreas problems. Additionally, disclose any risk factors for ketoacidosis, such as type 1 diabetes, changes in diet, reduced appetite, or upcoming surgery. Also, inform your doctor about all other medications or supplements you are taking, as they may interact with Kombiglyze XR 5mg/500mg Tablet. If you are planning to conceive, are pregnant, or breastfeeding, consult your doctor to discuss any potential risks to the baby.
Who should not take Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet is not recommended for individuals with severe kidney problems, those on dialysis, or those who are allergic to the medication. Additionally, it is not suitable for people trying to conceive, those who are pregnant, or breastfeeding, as it may pose a risk to the baby.
Does Kombiglyze XR 5mg/500mg Tablet cause weight gain?
No, Kombiglyze XR 5mg/500mg Tablet is not known to cause weight gain by itself. However, maintaining a healthy weight is crucial for managing diabetes. If you experience weight gain while taking Kombiglyze XR 5mg/500mg Tablet, consult your doctor for guidance.
Is Kombiglyze XR 5mg/500mg Tablet bad for your kidneys?
Kombiglyze XR 5mg/500mg Tablet is not harmful to your kidneys if your kidney function is normal. However, if you have or have had kidney problems, it is essential to inform your doctor, as they may require dose modification.
Do I still have to manage my diet and exercise while on Kombiglyze XR 5mg/500mg Tablet?
Yes, it is crucial to manage your diet and exercise while taking Kombiglyze XR 5mg/500mg Tablet. In addition to medication, a well-balanced diet and regular physical activity are essential for effectively managing blood sugar levels. Consult a dietitian to develop a personalized diet plan, and aim for at least 30 minutes of moderate-intensity exercise, such as a brisk walk, daily.
Can my blood sugar levels go too low on Kombiglyze XR 5mg/500mg Tablet?
Yes, it is possible for your blood sugar levels to become too low (hypoglycemia) while taking Kombiglyze XR 5mg/500mg Tablet, especially if you are taking other antidiabetic medications or insulin. Factors that may increase the risk of hypoglycemia include skipping meals, exercising excessively, or taking an overdose of the medication. If you experience symptoms of hypoglycemia, such as anxiety, sweating, weakness, tremors, or a fast heartbeat, consult your doctor for guidance.
What is the most important information I should know about Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet is generally safe when taken as directed. However, rare but serious side effects can occur, including pancreatitis, which can be severe and even life-threatening. If you experience persistent stomach pain, stop taking the medication and consult your doctor immediately. Additionally, inform your doctor about any pre-existing heart problems, as Kombiglyze XR 5mg/500mg Tablet may increase the risk of heart failure.
What will happen if I accidentally take more than the prescribed dose of Kombiglyze XR 5mg/500mg Tablet?
If you take more than the prescribed dose of Kombiglyze XR 5mg/500mg Tablet, your blood sugar levels may become too low (hypoglycemia). Monitor your blood sugar levels frequently for the next 24 hours. Mild episodes of hypoglycemia can usually be treated with sugary foods or drinks, but more severe episodes may require immediate medical attention. Consult your doctor for guidance on managing hypoglycemia.
How long do I need to take Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet only helps to manage your blood sugar levels but does not cure diabetes. Continue taking the medication as long as your doctor recommends it, as it is essential for maintaining good blood sugar control. Do not stop taking Kombiglyze XR 5mg/500mg Tablet without consulting your doctor, as this may lead to serious complications.
What if I miss a dose of Kombiglyze XR 5mg/500mg Tablet?
If you miss a dose of Kombiglyze XR 5mg/500mg Tablet and it is less than 12 hours since the scheduled dose, take the missed dose as soon as you remember. However, if it is more than 12 hours since the scheduled dose, take the next dose as usual and skip the missed dose. Do not take a double dose to make up for the missed dose, as this may increase the risk of side effects.
Is Kombiglyze XR 5mg/500mg Tablet safe to be taken for a long term?
Yes, Kombiglyze XR 5mg/500mg Tablet is safe for long-term use. Its long-term use, which can continue for months, years, or even lifelong, has not shown any harmful effects. Continue taking Kombiglyze XR 5mg/500mg Tablet as long as your doctor recommends it, as it is essential for maintaining good blood sugar control and managing diabetes.
