Janumet 50mg/500mg Tablet
Manufacturer
MSD Pharmaceuticals Pvt Ltd
Salt Composition
Metformin (500mg) + Sitagliptin (50mg)
Key Information
Short Description
Janumet 50mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus.
Dosage Form
Tablet
Introduction
Janumet 50mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Janumet 50mg/500mg Tablet is to be taken with food.
How it works
Janumet 50mg/500mg Tablet is a combination of two medicines: sitagliptin and metformin. Sitagliptin helps your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.
Quick Tips
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone. Take it with food to lower your chance of having an upset stomach. Take it in addition to regular exercise and healthy diet to lower levels of blood sugar. Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. Monitor your blood sugar level regularly while you are taking this medicine.
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Frequently asked questions
What is Janumet 50mg/500mg Tablet?
Janumet 50mg/500mg Tablet is a combination of two medicines: Sitagliptin and Metformin. It is used to treat type 2 diabetes mellitus in adults, improving blood glucose levels when taken with a proper diet and regular exercise. Metformin works by lowering glucose production in the liver and improving insulin sensitivity, while Sitagliptin inhibits the enzyme DPP4 and increases insulin release from the pancreas. This combination is not recommended for patients under 18 years of age.
Can the use of Janumet 50mg/500mg Tablet lead to Vitamin B12 deficiency?
Yes, the use of Janumet 50mg/500mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach, potentially leading to anemia and nerve problems. Symptoms may include tingling sensations and numbness in the hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance. To avoid these issues, it is recommended to take Vitamin B12 supplements at least once a year.
What are the possible side effects of Janumet 50mg/500mg Tablet?
Common side effects of Janumet 50mg/500mg Tablet include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rare but serious side effects include lactic acidosis, which can be life-threatening. Long-term use may also lead to Vitamin B12 deficiency.
Are there any specific conditions in which Janumet 50mg/500mg Tablet should not be taken?
Janumet 50mg/500mg Tablet should be avoided in patients with known allergies to its components or excipients, severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Is it safe to take alcohol while taking Janumet 50mg/500mg Tablet?
No, it is not safe to consume alcohol while taking Janumet 50mg/500mg Tablet, as it can increase the risk of lactic acidosis.
What are the instructions for storage and disposal of Janumet 50mg/500mg Tablet?
Store Janumet 50mg/500mg Tablet in its original container, tightly closed, according to the instructions on the pack or label. Dispose of unused medicine and ensure it is not consumed by pets, children, or other people.
Can the use of Janumet 50mg/500mg Tablet lead to lactic acidosis?
Yes, the use of Janumet 50mg/500mg Tablet can lead to lactic acidosis, a medical emergency characterized by increased levels of lactic acid in the blood. Symptoms may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, stop taking the medication and consult your doctor immediately.
