


Jaknat Tablet
Manufacturer
Natco Pharma Ltd
Salt Composition
Tofacitinib (5mg)
Key Information
Short Description
Jaknat Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis.
Dosage Form
Tablet
Introduction
Jaknat Tablet may be prescribed by itself or in combination with another medicine. The tablets can be taken with or without food and it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jaknat Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Information
Side Effects
Upper respiratory tract infections Headache Diarrhea Nasopharyngitis
Alcohol Warning
Consuming alcohol with Jaknat Tablet does not cause any harmful side effects.
Breastfeeding Warning
Jaknat Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Jaknat Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Jaknat Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme Janus kinase. This decreases the activity of the immune system and inflammation associated with rheumatic diseases and ulcerative colitis.
Quick Tips
Jaknat Tablet is used alone or in combination with other medicines for the treatment of rheumatoid arthritis that did not improve with other anti-rheumatic drugs. It may take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed. Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels. Jaknat Tablet can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches. Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
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Frequently asked questions
What precautions should I take if I have liver problems before taking Jaknat Tablet?
Inform your doctor if you have liver problems before starting Jaknat Tablet. This is because Jaknat Tablet may cause an increase in liver enzymes in some cases. Your liver function needs to be investigated before starting Jaknat Tablet. Although, Jaknat Tablet can be given to patients with mild to moderate liver function impairment, but it should not be prescribed to patients with severe liver impairment.
Can Jaknat Tablet increase the risk of developing cancer?
Yes, Jaknat Tablet may increase the risk of developing certain cancers, including lymphoma and skin cancers, by affecting the working of the immune system. Inform your doctor if you ever had or have any type of cancer.
What is Jaknat Tablet used for?
Jaknat Tablet is approved for use in people with moderate to severe rheumatoid arthritis, an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient. It can also be used earlier in treatment if the person does not respond well to the prescribed drugs. It can be used alone or together with some other medicines, such as methotrexate.
How long does it take for Jaknat Tablet to start working?
Jaknat Tablet usually takes about 2 to 8 weeks before you start feeling better, and it can take 3 to 6 months to feel the maximum effect of this medication.
Do I need to get any investigations done before starting Jaknat Tablet?
You may need to get your blood tests done before you start Jaknat Tablet or while you are taking it. Blood tests are done to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Jaknat Tablet is not causing problems. Your doctor may also advise you to get tested for tuberculosis before starting Jaknat Tablet, as using Jaknat Tablet may make an existing infection worse.
Can Jaknat Tablet cause infections?
Yes, Jaknat Tablet is a medicine that affects your immune system. This may reduce your ability to fight infection and may increase the risk of getting a serious infection, including tuberculosis. It may also include infections caused by severe fungal, bacterial or viral infections that spread through the body. In some cases, these infections can be life-threatening and may even cause death. Hence, it is advised to treat these infections in a hospital.
Can I take Jaknat Tablet if I am already taking tocilizumab?
No, you should not take tocilizumab along with Jaknat Tablet. Jaknat Tablet affects the immune system, so you should avoid taking it with any other immunity-affecting medicine. Taking both medicines together can further increase the risk of infection and may lead to further complications.