


Isocret 20 Tablet
Manufacturer
Accretion Pharmaceuticals
Salt Composition
Isotretinoin (20mg)
Key Information
Short Description
Isocret 20 Tablet belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.
Dosage Form
Tablet
Introduction
Isocret 20 Tablet should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isocret 20 Tablet is to be taken with food.
Safety Information
Side Effects
It may cause dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.
Alcohol Warning
Caution is advised when consuming alcohol with Isocret 20 Tablet. Please consult your doctor.
Breastfeeding Warning
Isocret 20 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Isocret 20 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
How it works
Isocret 20 Tablet is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).
Quick Tips
You have been prescribed Isocret 20 Tablet for the treatment of severe acne. Take it with food. Avoid exposure to sunlight while using Isocret 20 Tablet. Use protective measures such as sunscreen or protective clothing. Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile. It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
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Frequently asked questions
Is Isocret 20 Tablet safe to use?
Isocret 20 Tablet requires caution due to its potential for significant adverse reactions. It should only be used in patients with severe nodular acne who are unresponsive to conventional treatments, including systemic antibiotics. Furthermore, it is not recommended for pregnant women due to the high risk of severe birth defects.
Is Isocret 20 Tablet a steroid?
No, Isocret 20 Tablet is a retinoid (vitamin A) used to treat severe acne.
What are the recommended tests during Isocret 20 Tablet therapy?
Before treatment initiation, liver enzymes and serum lipids should be assessed. Monitoring these levels will occur after one month of treatment, then at 3-month intervals unless clinical indications warrant more frequent monitoring.
Is the effect of Isocret 20 Tablet permanent?
Many patients experience lasting improvement following a 15-20-week course with Isocret 20 Tablet, effectively curing the condition and preventing recurrence. If a second course is necessary, it must be delayed for at least eight weeks after completing the first.
Why is Isocret 20 Tablet so dangerous during pregnancy?
Using Isocret 20 Tablet while pregnant poses an extremely high risk of severe birth defects in the baby. This risk warrants immediate discontinuation.
Can Isocret 20 Tablet cause cancer?
There is no evidence suggesting Isocret 20 Tablet causes cancer, and it may even be used to treat some types of head, skin, and neck cancers.
What are the long-term side effects of Isocret 20 Tablet?
The standard course of treatment for Isocret 20 Tablet is 15–20 weeks. Long-term effects of low doses have not been extensively studied, but it may impact bone mineral density and increase the risk of osteoporosis or fractures.
Does Isocret 20 Tablet affect male fertility?
Isocret 20 Tablet does not negatively affect male fertility. No significant effects on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose were observed.
Does Isocret 20 Tablet damage your liver?
Isocret 20 Tablet may temporarily elevate liver enzymes. Therefore, regular laboratory testing is essential during treatment. If the liver enzyme levels remain elevated for a prolonged time, your doctor may need to stop using Isocret 20 Tablet.