


Huminsulin N 40IU/ml Injection
Manufacturer
Eli Lilly and Company India Pvt Ltd
Salt Composition
Insulin Isophane (40iu)
Key Information
Short Description
Huminsulin N 40IU/ml Injection is used to improve blood sugar control in adults and children with type 1 and type 2 diabetes mellitus. It is an intermediate-acting type of insulin that helps to lower blood sugar levels and reduce the chances of developing serious complications of diabetes.
Dosage Form
Injection
Introduction
Huminsulin N 40IU/ml Injection is often prescribed along with short-acting insulin or other oral diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. Don’t stop taking it unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results, and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Safety Information
Side Effects
Hypoglycemia (low blood sugar level) Reactions at the injection site like redness or swelling Lipodystrophy (skin thickening or pits at the injection site) Edema (swelling over the whole body due to fluid retention) Weight gain
Alcohol Warning
It is unsafe to consume alcohol with Huminsulin N 40IU/ml Injection.
Breastfeeding Warning
Huminsulin N 40IU/ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Pregnancy Warning
Huminsulin N 40IU/ml Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Interacting Medicines
Benazepril Captopril Enalapril Fosinopril
How it works
Huminsulin N 40IU/ml Injection is an intermediate-acting insulin that starts working in 1-2 hours after injection. It works similar to the insulin that is produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver. This helps to lower the blood sugar levels in diabetes mellitus.
Quick Tips
Hypoglycemia (low blood sugar level) is a common side effect. Hence regular monitoring of blood sugar levels is required while taking this medicine. Injection below the skin of the abdomen results in faster absorption than other injection sites. Injection sites must be rotated to prevent hard lumps from developing at one site. Opened vials/cartridge are good at room temperature for up to 4 weeks while unopened vials must be placed in the refrigerator (2°C–8°C).
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Frequently asked questions
How does biphasic isophane insulin work?
Biphasic isophane insulin is a type of human insulin analogue (a modified version of naturally produced insulin made in a laboratory) that acts like the body's natural insulin. It’s designed to release insulin gradually, providing a balanced blood sugar level over time and helping cells absorb glucose for energy. It starts working within an hour or two after injection and reaches peak activity in 7 hours, followed by a gradual reduction of its effects. The overall duration of action is typically 18 to 24 hours.
What is Huminsulin N 40IU/ml Injection? How is it made?
Huminsulin N 40IU/ml Injection is a man-made version of human insulin produced using biotechnology techniques called recombinant DNA technology. It’s available as a sterile, clear, and colorless solution containing insulin aspart along with other additives such as glycerin, phenol, metacresol, zinc, sodium chloride etc.
Can Huminsulin N 40IU/ml Injection cause hypoglycemia? How do I prevent it?
Yes. The most common side effect of Huminsulin N 40IU/ml Injection is hypoglycemia (low blood sugar). This is often a concern if you skip meals, consume alcohol, over-exercise, or take other diabetes medications alongside this injection. Therefore, it’s important to eat regular meals and avoid skipping them. If you experience hypoglycemia symptoms, such as confusion, dizziness, or fatigue, immediately consume glucose tablets, honey, or fruit juice. Seek immediate medical advice if these symptoms are severe or persist. Regular blood sugar monitoring is essential.
What are the other side effects of Huminsulin N 40IU/ml Injection? How to prevent them?
Common side effects include injection site reactions like redness, itching, pain, and swelling. These usually subside on their own without requiring treatment. Rarely, insulin injections can lead to lipodystrophy, which means changes in fat tissue due to repetitive needle use. This may occur as a result of lipohypertrophy (thickening of adipose tissue) or lipoatrophy (thinning of adipose tissue). It's essential to rotate your injection sites, changing locations regularly and avoiding injecting into the same spot repeatedly.
How should Huminsulin N 40IU/ml Injection be used?
Huminsulin N 40IU/ml Injection is administered subcutaneously (under the skin) using a syringe or pen device. Your doctor will demonstrate how to inject at an appropriate location on your body. To reduce lipodystrophy risk, it's crucial to rotate injection sites every few weeks. Always use a different injection site each week.
Is Huminsulin N 40IU/ml Injection given as an injection into a vein (intravenous)?
In some cases, especially during severe diabetic ketoacidosis or hyperglycemia, Huminsulin N 40IU/ml Injection may be administered intravenously. This is only done in hospital settings by healthcare professionals under constant blood sugar monitoring.
Is Huminsulin N 40IU/ml Injection safe to use during pregnancy?
Huminsulin N 40IU/ml Injection can be safely used during pregnancy when prescribed by a doctor. It is essential to inform your healthcare professional if you are pregnant, planning pregnancy, or breastfeeding before starting treatment with Huminsulin N 40IU/ml Injection. Your dosage may need adjustments, and regular blood sugar monitoring might be necessary.
When does the dosage of Huminsulin N 40IU/ml Injection need to be changed?
Your doctor should evaluate your individual case. You might need dose modifications if you experience significant changes in weight, stress levels, illness, or dietary habits, such as skipping meals. If any unexpected side effects occur, seeking guidance from your healthcare professional is essential.