Herhope 150mg Injection
Manufacturer
Torrent Pharmaceuticals Ltd
Salt Composition
Trastuzumab (150mg)
Key Information
Short Description
Herhope 150mg Injection is used in the treatment of breast and stomach cancer.
Dosage Form
Injection
Introduction
Herhope 150mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Safety Information
Side Effects
The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection.
Alcohol Warning
Herhope 150mg Injection may cause excessive drowsiness with alcohol.
Breastfeeding Warning
Herhope 150mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Herhope 150mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Herhope 150mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.
Quick Tips
It is given as an injection into your vein or under the skin, usually over 1 hour. Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment. Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shivering, swelling of legs and arm. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Frequently asked questions
What are the serious side effects of Herhope 150mg Injection?
Serious adverse reactions can occur with Herhope 150mg Injection, including sore throat, fever, chills, fatigue, pallor, nosebleeds, and other unusual bruising or bleeding. There may also be gastrointestinal discomfort such as stomach pain, seizures, hallucinations, muscle cramps, and spasms. Nausea or vomiting, loss of appetite, and fatigue can also occur during treatment. Additionally, patients might experience changes in urine appearance (e.g., discoloration) along with decreased urine output, difficulty urinating, pain during urination, and signs of infection. If you experience any of these symptoms, contact your healthcare provider immediately.
When can I get pregnant after Herhope 150mg Injection therapy?
It is crucial for women of child-bearing age to use effective contraception during Herhope 150mg Injection therapy and for seven months following treatment completion. After this period, you may plan for pregnancy when your doctor deems it appropriate.
How long should I take Herhope 150mg Injection?
Patients with early breast cancer are advised to receive Herhope 150mg Injection for one year or until the disease recurrence, whichever happens first. Extending treatment beyond one year is not recommended in patients with early-stage breast cancer.
Is fasting required before administering Herhope 150mg Injection?
No, fasting is not necessary before administering Herhope 150mg Injection. It should only be administered under the supervision of a doctor experienced in giving chemotherapy and should always be done under the guidance of a healthcare professional.
How is Herhope 150mg Injection administered: intravenously or intramuscularly?
Herhope 150mg Injection is available in two formulations for administration. One is an intravenous infusion, and the other is an injection under the skin (subcutaneous). It's important to verify the correct formulation before administering the medication as prescribed by your doctor. Always follow the instructions on the product label for specific details regarding administration.
Can Herhope 150mg Injection be given to HER2 negative cancer patients?
No, Herhope 150mg Injection is not intended for use in patients with HER2-negative cancer. It is a monoclonal antibody that selectively binds to the protein known as human epidermal growth factor receptor 2 (HER2). Her hope 150mg injection is primarily effective for HER2-positive patients, as it prevents cancer cell growth and spread. In patients without HER2 expression, this medication will not offer therapeutic benefits.
Why are heart investigations recommended before and during Herhope 150mg Injection therapy?
Herhope 150mg Injection, when used with anthracycline-based anti-cancer medications (such as doxorubicin), may impact your heart. Therefore, it's essential to have a pre-treatment heart assessment to evaluate your cardiac health and monitor for potential complications. This evaluation should be repeated at regular intervals throughout treatment.
How often should I have my heart checked during Herhope 150mg Injection therapy?
The frequency of cardiac investigations for patients undergoing Herhope 150mg Injection is as follows: At the beginning of treatment, and every three months throughout the duration of treatment. After discontinuation of treatment, they need to be performed every six months until two years after the final administration. Patients with pre-existing heart conditions will require regular evaluations every twelve weeks.
