Herduo Tablet
Manufacturer
Natco Pharma Ltd
Salt Composition
Lapatinib (250mg)
Key Information
Short Description
Herduo Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells.
Dosage Form
Tablet
Introduction
Herduo Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Herduo Tablet is to be taken empty stomach
Safety Information
Side Effects
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools
Alcohol Warning
It is not known whether it is safe to consume alcohol with Herduo Tablet. Please consult your doctor.
Breastfeeding Warning
Herduo Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Herduo Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Herduo Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways
Quick Tips
It should be taken 1 hour before or 2 hours after the meal preferably at the same time every day Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it Monitor your blood pressure regularly while taking this medication Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting Do not take this medicine if you are pregnant, planning to conceive or breastfeeding
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Frequently asked questions
Is Herduo Tablet a chemotherapy medicine?
No, Herduo Tablet is a targeted drug that belongs to a class of anti-cancer medicines. These medicines are more specific than chemotherapy in their mechanisms of action. Herduo Tablet belongs to the tyrosine kinase inhibitor group of medicines. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.
Can Herduo Tablet be given in combination with other anti-cancer drugs?
Yes, Herduo Tablet can be used in combination with other anti-cancer drugs. It is typically combined with capecitabine to treat advanced breast cancer in patients who have already been treated with chemotherapy. Herduo Tablet is also used with letrozole to treat breast cancer in post-menopausal women.
How should I take Herduo Tablet?
Take Herduo Tablet exactly as directed by your doctor. Swallow the tablet whole with a glass of water at the same time each day. You must take Herduo Tablet 1 hour before or 1 hour after meals and at the same time concerning food each day (e.g., you could always take your tablet one hour before breakfast).
Does Herduo Tablet have any effect on my liver?
Herduo Tablet may cause liver damage, which can be severe or life-threatening. Liver damage can occur as early as several days after starting treatment with Herduo Tablet or later on. Tell your doctor if you have liver disease. If you experience symptoms such as itching, changes in skin or eye color (yellowing), discoloration of urine, pain in the upper right part of your stomach, unusual bleeding or bruising, or pale or dark stools, call your doctor immediately.
How can I manage diarrhea while taking Herduo Tablet?
If you experience diarrhea while taking Herduo Tablet, drink plenty of fluids (8 to 10 glasses a day) such as water, sports drinks, or other clear liquids. Eat low-fat, high protein foods instead of fatty or spicy foods. Cooking vegetables instead of eating raw vegetables and removing the skin from fruits before eating may also help. Try to avoid milk and dairy products (including ice cream) and herbal supplements (some may cause diarrhea). If the condition persists, inform your doctor who may interrupt treatment depending on the severity of diarrhea.
How should I take care of my skin while on Herduo Tablet?
Your doctor will check your skin before and during treatment. If you have sensitive skin, use a soap-free cleanser and beauty products that are fragrance-free and hypoallergenic. It's recommended to use sunscreen with an SPF (Sun Protection Factor) of 30 or higher. Inform your doctor immediately if you develop a rash.
What tests will the doctor advise before starting Herduo Tablet?
You may need additional tests to check if your heart and liver are functioning properly. Herduo Tablet can change how your heart beats and pumps blood through your body. Your doctor will monitor you carefully to see if Herduo Tablet has affected your heart. Along with that, your doctor will get your liver function investigated. Based on the results of these tests, the doctor will decide whether dose adjustment or discontinuation of treatment is required.
How long after Herduo Tablet can I plan pregnancy?
Use an effective method of contraception to prevent pregnancy while you are taking Herduo Tablet and continue for at least one week after the last dose. Inform your doctor if you become pregnant, who will determine whether to stop or continue treatment.
