Herduo Tablet
Manufacturer
Natco Pharma Ltd
Salt Composition
Lapatinib (250mg)
Key Information
Short Description
Herduo Tablet is used in the treatment of breast cancer by stopping or slowing down the growth of cancer cells.
Dosage Form
Tablet
Introduction
Herduo Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea; drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Herduo Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Herduo Tablet is to be taken on an empty stomach.
How it works
Herduo Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways.
Quick Tips
It should be taken 1 hour before or 2 hours after the meal, preferably at the same time every day. Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools. Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting. It may cause serious bleeding problems. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools. Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
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Frequently asked questions
Is Herduo Tablet a chemotherapy medicine?
No, Herduo Tablet is a targeted drug that belongs to a class of anti-cancer medicines. It works by blocking the action of abnormal proteins that signal cancer cells to multiply, helping stop or slow the spread of cancer cells. These mechanisms differ from the broader approach of chemotherapy.
Can Herduo Tablet be given in combination with other anti-cancer drugs?
Yes, Herduo Tablet can be used in combination with other anti-cancer drugs. It is commonly used in combination with capecitabine to treat advanced breast cancer in patients who have already been treated with chemotherapy. Herduo Tablet can also be combined with letrozole to treat breast cancer in postmenopausal women.
How should I take Herduo Tablet?
You must swallow Herduo Tablet tablets whole with a glass of water at the same time each day. It is important to take Herduo Tablet 1 hour before or 1 hour after meals and at the same time regarding food each day (e.g., you could always take your tablet one hour before breakfast). Follow your doctor's instructions closely.
Does Herduo Tablet have any effect on my liver?
Herduo Tablet may cause liver damage, which can be severe or life-threatening. Liver damage can occur as early as several days after starting treatment or months later. If you have liver disease, inform your doctor before starting Herduo Tablet. If you experience symptoms such as itching, discoloration of the skin or eyes (yellowing), discoloration of urine, pain in the upper right stomach, unusual bleeding or bruising, or pale or dark stools, contact your doctor immediately.
How should I manage diarrhea while taking Herduo Tablet?
If you experience diarrhea while taking Herduo Tablet, drink plenty of fluids (8 to 10 glasses a day) such as water, sports drinks, or other clear liquids. Choose low-fat, high protein foods instead of fatty or spicy ones. Eating cooked vegetables instead of raw vegetables and removing the skin from fruits before eating can also help. Try to avoid milk and milk products, including ice cream, and herbal supplements (some may cause diarrhea). If the condition persists, inform your doctor who may adjust your treatment accordingly based on the severity.
How can I take care of my skin while on Herduo Tablet?
Your doctor will check your skin before and during the treatment. If you have sensitive skin, use a soap-free cleanser and beauty products that are fragrance-free and hypoallergenic. It is also advised that you wear sunscreen with an SPF (Sun Protection Factor) of 30 or higher. If you experience a rash, immediately inform your doctor.
What tests will the doctor advise before starting Herduo Tablet?
Before starting Herduo Tablet, your doctor may order additional tests to evaluate heart and liver function. Herduo Tablet might affect your heart's rhythm and how well your heart pumps blood. Your doctor will monitor you closely to ensure there are no adverse effects on your heart or liver. Your doctor may also conduct a liver function investigation based on the test results.
How long after Herduo Tablet can I plan pregnancy?
To avoid pregnancy while taking Herduo Tablet, use an effective contraceptive method for at least 1 week after finishing the last dose. If you become pregnant, inform your doctor as they will make a decision about continuing or stopping treatment.
