Grikli-M1 Tablet SR
Manufacturer
Prector Lifesciences
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Grikli-M1 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults, helping to control blood sugar levels.
Dosage Form
Tablet SR
Introduction
Grikli-M1 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grikli-M1 Tablet SR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Grikli-M1 Tablet SR.
Breastfeeding Warning
Grikli-M1 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Grikli-M1 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Grikli-M1 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Grikli-M1 Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Grikli-M1 Tablet SR?
Store Grikli-M1 Tablet SR in its original container, tightly closed, according to the instructions provided on the packaging or label. Dispose of any unused medication and ensure it is not accessible to pets, children, or other individuals.
Can the use of Grikli-M1 Tablet SR lead to lactic acidosis?
Yes, Grikli-M1 Tablet SR can cause lactic acidosis, a medical emergency characterized by elevated blood lactate levels. This rare side effect is more likely to occur in patients with underlying kidney disease, the elderly, or those who consume large amounts of alcohol. Symptoms may include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, or slow heart rate. If you experience these symptoms, discontinue Grikli-M1 Tablet SR and consult your doctor immediately.
What is Grikli-M1 Tablet SR?
Grikli-M1 Tablet SR is a combination medication containing Glimepiride and Metformin. It is used to treat type 2 diabetes mellitus (DM) in adults, in conjunction with a healthy diet and regular exercise. Glimepiride increases insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Grikli-M1 Tablet SR?
Common side effects of Grikli-M1 Tablet SR include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects include lactic acidosis. Long-term use may also lead to Vitamin B12 deficiency. Consult your doctor if you experience any unusual symptoms.
Can the use of Grikli-M1 Tablet SR lead to Vitamin B12 deficiency?
Yes, Grikli-M1 Tablet SR can cause Vitamin B12 deficiency on long-term use, as it interferes with stomach absorption. Untreated deficiency may lead to anemia, nerve problems, and symptoms such as tingling sensations, numbness, weakness, urinary issues, changes in mental status, and balance difficulties. To avoid these issues, consider taking Vitamin B12 supplements at least once a year.
Can the use of Grikli-M1 Tablet SR cause hypoglycemia?
Yes, Grikli-M1 Tablet SR can cause hypoglycemia, characterized by symptoms such as nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, and feelings of anxiety or shakiness. This is more likely to occur if you miss or delay meals, consume alcohol, over-exercise, or take other antidiabetic medications. Regular blood sugar monitoring is essential. Always carry a quick source of sugar, such as glucose tablets, honey, or fruit juice.
Is it safe to take alcohol while I am also taking Grikli-M1 Tablet SR?
No, it is not recommended to consume alcohol while taking Grikli-M1 Tablet SR, as it may lower blood sugar levels and increase the risk of hypoglycemia and lactic acidosis.
