Grikli M 2mg/500mg Tablet
Manufacturer
Prector Lifesciences
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Grikli M 2mg/500mg Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
Grikli M 2mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grikli M 2mg/500mg Tablet is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Grikli M 2mg/500mg Tablet.
Breastfeeding Warning
Grikli M 2mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Grikli M 2mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Grikli M 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
You should continue to exercise regularly Eat a healthy diet Take your other diabetes medicines along with Grikli M 2mg/500mg Tablet. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine.
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Frequently asked questions
What are the recommended storage conditions for Grikli M 2mg/500mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can the use of Grikli M 2mg/500mg Tablet lead to lactic acidosis?
Yes, the use of Grikli M 2mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency that causes an increase in lactic acid levels in the blood. This condition is known as MALA (Metformin-associated lactic acidosis). While rare, it has been associated with patients who have underlying kidney disease, are older in age or use large amounts of alcohol. Symptoms of lactic acidosis can include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you experience these symptoms, immediately stop taking Grikli M 2mg/500mg Tablet and consult your doctor.
What is Grikli M 2mg/500mg Tablet?
Grikli M 2mg/500mg Tablet is a combination of two medicines: Glimepiride and Metformin. This medicine is used to treat type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose level by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Grikli M 2mg/500mg Tablet?
The use of Grikli M 2mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Long-term use can also lead to serious but rare side effects like lactic acidosis. It's also known to cause Vitamin B12 deficiency.
Can the use of Grikli M 2mg/500mg Tablet lead to Vitamin B12 deficiency?
Yes, the use of Grikli M 2mg/500mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Untreated vitamin B12 deficiency may lead to anemia and nerve problems, including tingling and numbness in hands and feet, weakness, urinary problems, changes in mental status and difficulty in maintaining balance (ataxia). To avoid such issues, it's recommended that patients take external sources of Vitamin B12 at least once a year.
Can the use of Grikli M 2mg/500mg Tablet cause hypoglycemia?
Yes, the use of Grikli M 2mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It's more likely to occur if you miss meals, drink alcohol, over-exercise or take other antidiabetic medications along with it. Regular monitoring of blood sugar is important. Always keep a source of quick sugar like glucose tablets, honey or fruit juice handy.
Is it safe to take alcohol while I am also taking Grikli M 2mg/500mg Tablet?
No, it is not safe to take Grikli M 2mg/500mg Tablet along with alcohol because it can lower your blood sugar levels and lead to hypoglycemia. It may also increase the risk of lactic acidosis.
