Graine Plus 40mg/10mg Tablet SR
Manufacturer
Apical Biologicals
Salt Composition
Propranolol (40mg) + Flunarizine (10mg)
Key Information
Short Description
Graine Plus 40mg/10mg Tablet SR is a combination of two medicines that helps in preventing migraine.
Dosage Form
Tablet SR
Introduction
Graine Plus 40mg/10mg Tablet SR should be taken on empty stomach but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Graine Plus 40mg/10mg Tablet SR is to be taken empty stomach.
How it works
Graine Plus 40mg/10mg Tablet SR is a combination of two medicines: Propranolol and Flunarizine which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).
Quick Tips
You have been prescribed Graine Plus 40mg/10mg Tablet SR for prevention of migraine headaches. Do not take it to treat an acute attack of migraine. Keep taking it regularly every day, even if you don't have any symptoms. It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Graine Plus 40mg/10mg Tablet SR affects you.
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Frequently asked questions
In which conditions is the use of Graine Plus 40mg/10mg Tablet SR contraindicated?
Graine Plus 40mg/10mg Tablet SR is contraindicated in patients with an allergy to any ingredients or excipients. This medication contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Additionally, the use of this medication should be avoided in patients with a history of depression or Parkinson's disease due to flunarizine's presence.
What are the instructions for the storage and disposal of Graine Plus 40mg/10mg Tablet SR?
Store Graine Plus 40mg/10mg Tablet SR in its original container, tightly closed. Follow the instructions on the packaging label or medication information leaflet regarding proper storage methods. Dispose of unused medication and prevent it from being consumed by pets, children, or others.
Can I stop taking Graine Plus 40mg/10mg Tablet SR when my symptoms are improved?
Graine Plus 40mg/10mg Tablet SR is prescribed as a prophylactic treatment to prevent migraine headaches. Do not discontinue medication without explicit guidance from your healthcare provider as stopping this medicine prematurely may lead to the return of migraine episodes. Sudden withdrawal of propranolol, present in this medication, can trigger symptoms like sweating, shaking, irregular or rapid heartbeat, worsening underlying angina, and increased risk of heart attack.
Can Graine Plus 40mg/10mg Tablet SR be used for the treatment of a migraine headache?
No, Graine Plus 40mg/10mg Tablet SR is not intended for treating an ongoing migraine. This medication provides preventative protection against future episodes of migraines.
